Research
My research interests generally involve correlated and longitudinal data analyses in the settings of pharmaceutical safety, medical informatics,
and epidemiology. While there are a number of challenges faced when analyzing data in these settings, I am interested in planned and unplanned selection mechanisms. Towards planned selection mechanisms, I am involved in the development of efficient outcome dependent sampling designs for longitudinal binary response data in cohort studies (2-phase studies for longitudinal data). Such designs can be highly efficient relative to standard analysis of the entire cohort, while only sampling a fraction of it. These designs are particularly useful when exposure ascertainment is highly expensive (e.g., in studies that examine gene or biomarker by environment interactions). Unplanned selection biases are everywhere in longitudinal data, and I have been focused generally on response history dependent mechanisms that leading to monotic and nonmonotonic missingness, time dependent confounding, and differential intensity of followup.
Recently published work
Schildcrout JS and Heagerty PJ. Marginalized Models for Moderate to Long Series of Longitudinal Binary Response Data, Biometrics, 63(2):322--331, June 2007.
Schildcrout JS, Sheppard L, Lumley T, Slaughter JC, Koenig JQ, and Shapiro GG. Ambient air pollution and asthma exacerbations in children: an eight-city analysis, Am J Epidemiol, 164(6):505--517, Sep 2006.
Trenga CA, Sullivan JH,
Schildcrout JS, Shepherd KP, Shapiro GG, Liu LJS, Kaufman JD, and Koenig JQ. Effect of particulate air pollution on lung function in adult and pediatric subjects in a Seattle panel study, Chest, 129(6):1614--1622, Jun 2006.
Schildcrout JS and Heagerty PJ. Regression analysis of longitudinal binary data with time-dependent environmental covariates: bias and efficiency, Biostatistics, 6(4):633--652, Oct 2005.
Kanter JW,
Schildcrout JS, and Kohlenberg RJ. In vivo processes in cognitive therapy for depression: Frequency and benefits, Psychotherapy Research, 15(4):366--373, 2005.
Denny JC, Spickard A, Miller RA,
Schildcrout JS, Darbar D, Rosenbloom ST, and Peterson JF. Identifying UMLS concepts from ECG Impressions using
KnowledgeMap, AMIA Annu Symp Proc, pages 196--200, 2005.
Sheppard L, Slaughter JC, Schildcrout JS, Liu LJS, and Thomas Lumley. Exposure and measurement contributions to estimates of acute air pollution effects, J Expo Anal Environ Epidemiol, 15(4):366--376, Jul 2005.
