Lily Wang Assistant Professor of Biostatistics Department of Biostatistics Vanderbilt University School of Medicine S-2323 Medical Center North Nashville, TN 37232-2158 lily.wang@vanderbilt.edu phone: (615) 343-3856 fax: (615) 343-4924

Research Interests

• Clinical Trials Methodology
• Design and Analysis of Microarray Experiments
• Statistical Methods for the Analysis of Biological Pathways
• Analysis of Repeated and Correlated Data

Education

      PhD in Biostatistics
      School of Public Health, the University of North Carolina at Chapel Hill
      Dissertation: Some Statistical Aspects of the Analysis of Genomic Sequences
      Advisor: Dr Pranab K Sen

      MS in Biostatistics
      School of Public Health, the University of North Carolina at Chapel Hill
      Advisor: Dr Gary G Koch

      BA in Mathematics
      School of Arts and Sciences, Temple University

Work Experience

      Assistant Professor 2004 - present
      Department of Biostatistics, Vanderbilt University

      Collaborative Plan Assignment

      Department of Neurology (Report)
      Department of Obstetrics and Gynecology (2004-2007) (Report)
      Kennedy Center for Human Development (Report)
      Conte Center Bioinformatics Core: Genes Controlling Assembly and Function of Serotonin Systems (Report)

      Microarray Projects (Report)
      Weekly Omics Clinics (link)

      Research Assistant, Student Consultant 1998 - 2004
      Biometric Consulting Lab, the Univeristy of North Carolina at Chapel Hill

Resources for Collaborative Research

      Departmental Policies on Collaboration, Consulting and Grants (Policy)
      Biostatistics Clinics (Clinics)
      How to Prepare Data for Statisticians  (courtesy of Daniel W. Byrne, Senior Associate in Biostatistics)
       10DataEntryCommandments.doc
       spreadsheetfromheaven.xls Spreadsheetfromhell.xls
       datadictionary.xls (courtesy of Dr Paul Harris)

Computer Skills

      SAS, SUDAAN, PERL, C, R, JAVA, UNIX

Publications

1. Wang L, Sen PK. Extreme Value Theory in Some Statistical Analysis of Genomic Sequences. Extremes 2005; 8(4):295-310.
2. Wang L, Zhang B, Wolfinger RD, Chen X. An Integrated Approach for the Analysis of Biological Pathways Using Mixed Models. PLoS Genetics; (In Press)
3. Malow BA, Crowe C, Henderson L, McGrew SG, Wang L, Song Y, Stone WL. A Sleep Habits Questionnaire for Children with Autism Spectrum Disorders. Journal of Child Neurology; (In Press)
4. Matrisciano F, Bonaccorso S, Ricciardi A, Panaccione I, Wang L, Ruberto A, Tatarelli R, Nicoletti F, Girardi P, Shelton RC. Changes in BDNF serum levels in patients with major depression disorder (MDD) after 6 months treatment with sertraline, escitalopram, or venlafaxine. Journal of Psychiatric Research; (In Press)
5. Malow BA, Foldvary-Schaefer N, Vaughn BV, Selwa LM, Chervin RD, Weatherwax KJ, Wang L, Song Y. Treating Obstructive Sleep Apnea in Adults with Epilepsy: A Randomized Pilot Trial. Neurology; (In Press)
6. Selwa LM, Marzec ML, Chervin RD, Weatherwax KJ, Vaughn BV, Foldvary-Schaefer N, Wang L, Song Y, Malow B. Sleep Staging and Respiratory Events in Refractory Epilepsy Patients: Is there a First Night Effect? Epilepsia (In Press)
7. Azar NJ, Wright AT, Wang L, Song Y, Abou-Khalil BW. Temporal Pattern of Oxcarbazepine and Phenytoin Withdrawal Seizures during Epilepsy Monitoring. Epilepsy Research; (In Press)
8. Bagai K, Wilson JR, Khanna M, Song Y, Wang L, Fisher MA. Electrophysiological Patterns of Diabetic Polyneuropathy. EMG Journal; (In Press)
9. Hutchinson KN, Song Y, Wang L, Malow BA. Analysis of Sleep Parameters in Patients with Obstructive Sleep Apnea studied in a Hospital vs. a Hotel-Based Sleep Center. Journal of Clinical Sleep Medicine; (In Press)
10. Azar NJ,Wright AT, Wang L, Song Y, Abou-Khalil BW. Oxcarbazepine Withdrawal Seizures during Epilepsy Monitoring. Neurology; (In Press)
11. Azar NJ, Tayah TF, Wang L , Song Y, Abou-Khalil BW. Post-ictal Breathing Pattern distinguishes Epileptic from Non-Epileptic Convulsive Seizures. Epilepsia 2008; 49(1):132-137.
12. Fu L, Wang L, Y Aphinyanaphongs, Aliferis CF. Comparison of Impact Factor, Clinical Query Filters, and Pattern Recognition Query Filters in Terms of Sensitivity to Topic. Stud Health Technol Inform. 2007 ;129 :716-20
13. Mcgrew S, Malow BA, Henderson L, Wang L, Song Y, Stone WL. A Developmental and Behavioral Questionnaire for Autism Spectrum Disorders. Pediatric Neurology 2007; 37(2):108-116
14. Bonnin A, Torii M, Wang L, Rakic P, Levitt P. Serotonin modulates the response of embryonic thalamocortical axons to netrin-1. Nature Neuroscience, 2007; 10: 588 - 597
15. Peltier AC, Consens FB, Sheikh K, Wang L, Song Y, Russell JW. Autonomic Dysfunction in Obstructive Sleep Apnea Is Associated with Impaired Glucose Regulation. Sleep Medicine 2007; 8(2): 149-155.
16. Malow BA, Maezec ML, Mcgrew SG, Wang L, Henderson LM, Stone WL, Characterizing Sleep in Children with Autism Spectrum Disorders: A Multidimensional Approach. Sleep 2006; 28(12): 1563-71.
17. Sloane PD, Beck R, Kowlowitz V, Blotzer AM, Wang L, Akins L, White-Chu F, Mitchell CM: Behavioral coding for evaluation of medical student communication: clarification or obfuscation? Academic Medicine 2004; 79(2):162-170.
18. Glowa P, Frasier PY, Wang L, Eaker K, Osterling W: What happens after we identify intimate partner violence? the family physician's perspective. Family Medicine Journal 2003; 35(10):730-736
19. Sloane PD, Zimmerman S, Suchindran C, Reed P, Wang L, Boustani M, Sudha S: The public health impact of Alzheimer's disease, 2000-2050: potential implication of treatment advances. Annual Review of Public Health 2002; 23: 213-231.
20. Herman-Giddens ME, Wang L, Koch GG: Secondary sexual characteristics in boys: estimates from the National Health and Nutrition Examination Survey III, 1988 - 1994. Archives of Pediatric Adolescent 2001;155(9):1022-1028.

Presentations

1. Design of clinical studies - case-control study, Vanderbilt University Neurology Department , Oct 12 2006.
2. How to Conduct Statistical Modeling. Research Skills Worksop, Vanderbilt General Clinical Research Center, Oct 15, 2004.
3. Statistical Modeling. Statistical Thinking in Biomedical Research Short Course, Vanderbilt University, Oct 21, 2004.
4. Critical Review of Published Microarray Studies for Cancer Outcome and Guidelines on Statistical Analysis and Reporting, Omics Clinic Journal Club, Feb 6, 2007, with Constantin Aliferis.
5. Pathways to the Analysis of Microarray Data, Statistics and Methodology Core Quantitative Training Series, Vanderbilt Kennedy Center for Human Development, Jan 17, 2007
6. On Methods for Gene Function Scoring as a Means of facilitating the Interpretation of Microarray Results, Omics Clinic Journal Club, Vanderbilt Biostatistics department, Aug 15 2006, with Bing Zhang.
7. Planning Microarray Experiments, Statistics and Methodology Core Quantitative Training Series, Vanderbilt Kennedy Center for Human Development, April 17, 2006.
8. Remote homology detection for biological sequences: theory and applications, Aug 21, 2006. Analysis of Complex Data Sets Conference, Vanderbilt Kennedy Center for Human Development, Aug 21 2006.
9. Some Statistical Aspects of Analysis of Genomic Sequences. (invited presentation) Twelfth Annual International Conference on Statistics, Combinatorics, Mathematics and Applications, Auburn, Alabama, December 2-4, 2005.
10. How to Approach Genetic Sequencing Databases - a Primer, Statistics and Methodology Core Quantitative Training Series, Vanderbilt Kennedy Center for Human Development, Sept 30, 2005.
11. Making Sense of DNA and Protein Sequences, Biostatistics Seminar Series, Vanderbilt Biostatistics Department, Sept 28, 2005.
12. Pharmacogenetics and Drug Development, Computational Genetics Journal Club, Vanderbilt University, April 15, 2005.
13. Approximating Pairwise Alignment Score Distributions. Spring Meeting of the Eastern North American Region of the International Biometric Society (ENAR), Pittsburgh, PA, Mar 20-23, 2005.
14. Some Statistical Aspects of Analysis of Genomic Sequences. Spring Meeting of the Eastern North American Region of the International Biometric Society (ENAR), Pittsburgh, PA, Mar 28-31, 2004.

Journals

Bioinformatics Journals
Nature Neuroscience
Nature Molecular Systems Biology
Nature Genetics
Nature Review Genetics

PLoS Computational Biology
PLoS Genetics
PLoS Biology
PLoS One

PNAS
Bioinformatics
Briefings in Bioinformatics
Nucleic Acids Research
J. Computational Biology

BMC Bioinformatics
Genome Biology
BMC Genomics
BMC Systems Biology

Biostatistics Journals link

Album

my trip to China (Oct 8-28, 2003)

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