Qingxia (Cindy) Chen, PhD Assistant Professor of Biostatistics
E-mail: cindy.chen@vanderbilt.edu Phone: 615.936.8058 Fax: 615.343.4924 Office: MCN D-2203	Vanderbilt University School of Medicine Department of Biostatistics 1161 21st Avenue South S-2323 Medical Center North Nashville, TN 37232-2158

Research Interests

• Statistical Analysis with Missing Data
• Survival Data Analysis
• Bayesian Statistics, Computing Statistics
• Clinical Trials, Health Service Research, and Longitudinal Data Analysis.
• Semiparametric/Nonparametric Method, Robust Analysis
• imaging data analysis, especially fMRI
• and More

Curriculum Vitae

CV in pdf

Publication

• Moul, D., Ombao H., Monk T., Chen Q., Begley A., Buysse D. (2002). ``Masking effects of posture and sleep onset on core body temperature: a circadian rhythm of bedtime temperature drops". Journal of Biological Rhythms, 17, 447-462.
• Hall M, Vasko R, Buysse D, Ombao H, Chen Q., Cashmere D, Kupfer D and Thayer J. (2004).``Acute Stress Affects Heart Rate Variability During Sleep". Journal of Psychosomatic Medicine, 66, 56-62.
• Chen Q., Ibrahim J. G. (2006) ``Semiparametric Models for Missing Covariate and Response Data in Regression Models". Biometrics, 62, 177-184.
• Joos D., Chen Q., Jirjis J., Johnson KB (2006). ``An Electronic Medical Record in Primary Care: Impact on Satisfaction, Work Efficiency and Clinic Processes". AMIA Annu Symp Proc, 394-8.
• Dexheimer J., Jones I., Chen Q., Talbot T., Mason D., Aronsky D. (2006). ``Providers' Beliefs, Attitutes, and Behaviors Prior to Implementing a Computerized Pneumococcal Vaccination Reminder.". Academic Emergency Medicine. Acad Emerg Med, 13(12), 1312-8.
• Chen Q., Zeng, D., Ibrahim, J. G. (2007) ``Sieve Maximum Likelihood Estimation for Missing Covariates in Regression Models". Journal of the American Statistical Association. Vol 102, 1309-1318.
• Devin J.K., Blevins L.S., Verity D.K., Chen Q., Bloodworth J.R., Covington J., Vaughan D.E. (2007) ``Markedly Impaired Fibrinolytic Balance Contributes to Cardiovascular Risk in Adults with Growth Hormone Deficiency". Journal of Clinical Endocrinology and Metabolism. 3633-3639.
• Chen Q., Ibrahim, J. G., Chen, M.-H., Senchaudhuri, P. (2008) ''Theory and Inference for Regression Models with Missing Response and Covariates". Journal of Multivariate Analysis. 99(6). 1302-31.
• Ali YS, Rembold KE, Wills MB, Chen Q., Ayers CR, Rembold CM. (2008) ``Clinical significance of mobile carotid echoes''. University of Virginia Journal of Medicine. Oct;4:29-34.
• Johnson K., Chark D., MSc, Chen Q., Broussard A., Rosenbloom T. (2008) ``Performing Without a Net: Transitioning Away From a Health Information Technology-Rich Training Environment". Academic Medicine. 83(12),
• Shinall M.C., Peters T.R. Zhu Y., Chen Q., Poehling K.A. (2008) ``Potential Impact of Accelerating the Primary Series of Pertussis Vaccine in Infants". Pediatrics. 122(5), 1021-6.
• Halasa N., Gerber M., Chen Q., Wright P., Edwards K.(2008) ``Safety and immunogenicity of trivalent inactivated influenza vaccine in infants". Journal of Infectious Diseases. 197(10), 1448-1454.
• Devin J.K., Vaughan D.E., Blevins L.S., Chen Q., Covington J., Verity D.K., Young P.P. (2008) ``Low-Dose Growth Hormone Administration Mobilizes Endothelial Progenitor Cells in Healthy Adults". Growth Hormone and IGF Research. 18(3), 253-263.
• Zeng, D., Chen Q., Ibrahim, J. G. (2009) ``Gamma frailty transformation models for multivariate survival times''. Biometrika. 96(2):277-291.
• Janssen K.J.M., Vergouwe Y., Donders A.R.T., Harrell F.E. Jr., Chen Q., Grobbee D.E., Moons K.G.M. (2009) ``Dealing with missing predictor values when applying clinical prediction models". Clin Chem. 2009 May;55(5):994-1001.
• Miller E.K., Khuri-Bulos N., Williams J.V. Shehabi A.A., Faouri S., Jundi I.A., Chen Q., Heil1 L., Mohamed1 Y., Morin L., Ali A., Halasa N.B. (2009) ``Human Rhinovirus C Associated with Wheezing in Hospitalized Children in the Middle East'',J Clin Virol., 46(1):85-9.
• Talbot H.K., Poehling K.A., Williams J.V., Zhu Y., Chen Q., McNabb? P., Edwards K.M., Griffin M.R. (2009) ``Influenza in Older Adults: Impact of Vaccination of School Children". Vaccine. 27(13):1923-7.
• Janssen, K.J.M., Donders, A.R.T., Harrell, F.E., Vergouwe, Y., Chen Q., Grobbee, D.E., Moons, K.G.M. (2010) ``Missing covariate data in medical research: To impute is better than to ignore ". J Clin Epidemiol. 63(7):721-7.
• Zeng, D., Chen Q.* (2010) ``Adjustment for Missingness Using Auxiliary Information in Semiparametric Regression". Biometrics. 66(1):115-22. * Corresponding Author.
• Stenner S.P., Chen Q., Johnson K.B. (2010) ``The Impact of an Electronic Prescribing Intervention on Generic Medication Prescribing Behavior'', J Am Med Inform Assoc. 17(6):681-8.
• Rosenbloom S., McNabb? T., Chen Q., An A., Hsu S., Dupont W. (2010) ``Specialized Pediatric Growth Charts For Electronic Health Record Systems: the example of Down Sysdrome''. AMIA Annu Symp Proc. 687-91.
• Petty, T., Callahan, S.T., Chen Q., Edwards, K.M., Dempsey, A. (2010) ``Assessment of Parental Acceptance of a Potential Cytomegalovirus Vaccine for Adolescent Females Vaccine''. Vaccine. 28(35):5686-90.
• Ali SA, Williams JV, Chen Q., Faori S, Shehabi A, Jundi EA, Khuri-Bulos N, Halasa N. (2010) ``Human Metapneumovirus in Hospitalized Children in Amman, Jordan''. J Medical Virology, 82:1012-6.
• Khuri-Bulos N, Williams JV, Shehabi AA, Faouri S, Al Jundi E, Abushariah O, Chen Q., Ali SA, Vermund S, Halasa NB. (2010) ``Burden of RSV in Hospitalized Infants and Young Children in Amman, Jordan'', Scand J Infect Dis., 42(5):368-74.
• Li J, Solus J, Chen Q., Rho YH, Milne G, Stein CM, Darbar D. (2010) ``Role of inflammation and oxidative stress in atrial fibrillation''. Heart Rhythm., 7(4):438-44
• Talbot H., Griffin M., Chen Q., Zhu Y., Williams J., Edwards K. (2011) ``Effectiveness of Seasonal Vaccine in Preventing Confirmed Influenza-Associated Hospitalizations in Community Dwelling Older Adults". Journal of Infectious Diseases. J Infect Dis. 203(4):500-8.
• Griffin M.R., Monto A.S., Belongia E.A., Treanor J.J., Chen Q., Chen J., Talbot H.K., Ohmit S.E., Coleman L.A., Lofthus G., Petrie J.G., Meece J.K., Hall C.B., Williams J.V., Gargiullo P., Berman L.S., and Shay D.K. (2011) ``Effectiveness of Non-adjuvanted Pandemic Influenza A (H1N1?) Vaccines in Preventing Medically Attended Pandemic Influenza Virus Associated Acute Respiratory Illness in 4 US Communities''. PLoS? One. 2011;6(8):e23085. Epub 2011 Aug 12.
• Xu H., Fu Z., Shah A., Chen Y., Peterson N., Chen Q., Mani S., Levy M., Dai Q., Denny J. (2011) ``Scanning Entire Electronic Health Records for Detecting Colorectal Cancer Cases''. AMIA Annu Symp Proc. Accepted.
• Johnson K.B., Unertl K.M., Chen Q., Lorenzi N.M., Nian H., Mrisse M., (2011) ``Health Information Exchange Usage in Ambulatory Settings: the Who, What and Why''. J Am Med Inform Assoc. 2011 Sep-Oct;18(5):690-7.
• Gadd C.S., Ho Y.-X., Cala C.M., Blakemore D., Chen Q., Frisse M., Johnson K.B., (2011) ``Users' perspectives on the usability of a regional health information exchange''. J Am Med Inform Assoc. 2011 Sep-Oct;18(5):711-6. Epub 2011 May 27.
• Zeng D., Chen Q., Chen M-H, Ibrahim J.G., the Amgen Research Group (2011) ``Estimating Treatment Effects with Treatment Crossovers via Semi-Competing Risks Models: An Application to a Colorectal Cancer Study''. Biometrika. 2012 99 (1): 167-184. R codes
• Xu H., Fu Z., Shah A., Chen Y., Peterson N., Chen Q., Mani S., Levy M., Dai Q., Denny J. (2011) ``Scanning Entire Electronic Health Records for Detecting Colorectal Cancer Cases''. AMIA Annu Symp Proc. 2011;2011:1564-72. Epub 2011 Oct 22.
• Frisse M., Johnson K., Nian H., Davidson C., Gadd C.S., Unertl K., Turri P.A., Chen Q., (2011) ``Financial Impact of Health Information Exchange on Emergency Department Care: A Case-Control Comparative Analysis''.
  J Am Med Inform Assoc. 2012 May 1;19(3):328-33. PMID: 22058169.
• Muldowney J.A.S., Chen Q.,, Blakemore D.L., Vaughan D.E., (2012) ``Pentoxifylline Lowers Plasminogen Activator Inhibitor-1 Levels in Obese Individuals: A Pilot Study''. Angiology. 2012 Feb 17. [Epub ahead of print]
• Smith J.P., Haddad E.V., Taylor M.B., Oram D., Blakemore D., Chen Q., Boutaud O., Oates J.A., (2012) ``Suboptimal Inhibition of Platelet Cyclooxygenase-1 by Aspirin in Metabolic Syndrome''. Hypertension. 2012 Mar;59(3):719-25.
• Wu H.*, Chen Q.*^, Ware L.B., Koyama T. (2012) ``A Bayesian Approach for Generalized Linear Model with an Independent Biomarker Measurement Variable Subject to Detection-Limit -- an Application to Acute Lung Injury``. Applied Statistics. To appear.
  * Co-first author; ^ corresponding author.

Collaboration and Methodology Work

• Protected Faculty Research Time -- 10%
• A New Approach to Correct Verification Bias Using Auxiliary Information -- 30%
• Teaching -- 5%
• Collaboration plan with DBMI -- 25%
• An in-silico method for epidemiological studies using Electronic Medical Records -- 10%
• Disseminating Adapted Diabetes Evidence to Clinicians Through a Patient Portal --10%
• My MediHealth? A Paradigm for Children-centered Medication Management -- 10%

Teaching

Epid 323 (Spring 2011): Design and Analysis with Time-to-Event Data

Epid 323 (Spring 2012): Design and Analysis with Time-to-Event Data

Education

PhD in Biostatistics 2005
Department of Biostatistics, School of Public Health, University of North Carolina at Chapel Hill
Dissertation: Theory and Inference for Parametric and Semiparametric Methods in Missing Data Problem

MS in Statistics 2001
Department of Statistics, School of Arts and Sciences, University of Pittsburgh

BA in Statistics 1999
Department of Statistics and Finance, University of Science and Technology of China, P.R.China