Zhiguo (Alex) Zhao, M.S.

Biostatistician III


Contact Information

Office Address :   571 Preston Research Building
VICC Cancer Biostatistics Center
Department of Biostatistics
Vanderbilt University
Phone :   615.936.0588
Fax :   615.936.2606
E-mail :   Alex.Zhao at Vanderbilt.Edu

Curriculum Vitae

My CV, Updated on November 03, 2011

Education

MS in Biostatistics, May 2008
The University of Iowa
MS in Applied Mathematics, May 2005
The University of Toledo

Area of Interest

  • Statistical Computing
  • Clinical Trials
  • Statistics in Epidemiology
  • Statistical Genetics
  • Bayesian Statistics
  • Missing Data Analysis
  • Mixed Eff ects Models
  • Time-to-event Analysis

Current Position

Biostatistician III May 2011 - present
Department of Biostatistics, Vanderbilt University

Previous Positions

Biostatistician II July 2008 - April 2011
Department of Biostatistics, Vanderbilt University

Student Biostatistical Consultant May 2007 - May 2008
Biostatistics Consulting Center, University of Iowa, IA

My Research Projects

My R Functions

Problems I Met and My Solutions

My Collaborative Projects

Peer-Reviewed Publications | PubMed

  1. Stabler S, Koyama T, Zhao Z, Martinez-Ferrer M, Allen RH, Luka Z, Loukachevitch LV, Clark PE, Wagner C, Bhowmick NA., Peter E. Clark, Conrad Wagner, Neil A. Bhowmick, ``Serum methionine metabolites are risk factors for metastatic prostate cancer progression". PLoS One. 2011;6(8) PMID:21853037.
  2. Richard L. White, Jr., MD, Gregory D. Ayers, MS, Zhiguo Zhao, MS, et al.. "Factors Predictive of the Status of Sentinel Lymph Nodes in Melanoma Patients from a Large Multicenter Database". Ann Surg Oncol. 2011 Jun 7. DOI 10.1245/s10434-011-1826-9; PMID:21647761.
  3. Esbenshade AJ, Ho RH, Shintani A, Zhao Z, Smith LA, Friedman DL. "Dapsone-induced methemoglobinemia: A dose-related occurrence?" Cancer. 2011 Jan 18. doi: 10.1002/cncr.25904; PMID:21246536.
  4. Leora Horn MD, Zhiguo Zhao MS, Janessa Laskin MD, Yu Shyr PhD, et al. ``A Phase II Study of Carboplatin and Irinotecan in Extensive Stage Small Cell Lung Cancer". Clinical Lung Cancer. 2011 May; 12(3): 165-1 PMID: 21663858.
  5. Lovvorn HN 3rd, Ayers D, Zhao Z, Hilmes M, Prasad P, Shinall MC Jr, Berch B, Neblett WW 3rd, O'Neill JA Jr. "Defining hepatoblastoma responsiveness to induction therapy as measured by tumor volume and serum alpha-fetoprotein kinetics". J Pediatr Surg. 2010 Jan;45(1):121-8; discussion 129. PMID:20105591
  6. Ogden SR, Noto JM, Allen SS, Patel DA, Romero-Gallo J, Washington MK, Fingleton B, Israel DA, Lewis ND, Wilson KT, Chaturvedi R, Zhao Z, Shyr Y, Peek RM Jr. "Matrix metalloproteinase-7 and premalignant host responses in Helicobacter pylori-infected mice". Cancer Res. 2010 Jan 1;70(1):30-5. PMID:20048070
  7. Zhiguo Zhao, MS, Deming, Sandry L. PhD., et al., "Dietary folate intake and breast cancer risk in the Nashville Breast Health Study". In preparation.
  8. Neeraja B. Peterson, Alicia Beegly-Fadiel, Zhiguo Zhao, et al.. "MMP-7 gene polymorphisms and breast cancer risk and survival in Caucasian women". In preparation.
  9. Stover DG, Cushman-Vokoun AM, Zhao Z, Koehler EA, Vnencak-Jones CL, Berlin J., et al., "Analysis of BRAF and KRAS mutations in colorectal cancer and rectal carcinogenesis via fluorescent allele-specific PCR". In preparation
  10. Sabrina C. Wentz, Zhiguo Zhao, Yu Shyr, Chanjuan Shi, Nipun B Merchant, M. Kay Washington, Fen Xia, A. Bapsi Chakravarthy. ``Lymph Node Ratio and Preoperative CA 19-9 Levels Predict Overall Survival and Recurrence-Free Survival in Patients with Resected Pancreatic Adenocarcinoma". In preparation.

Conference Abstracts/Posters

  1. Sabrina C. Wentz, Zhiguo Zhao, Yu Shyr, Fen Xia, Bapsi Chakravarthy, and M. Kay Washington. "Lymph Node Ratio, Total Node Count, and Preoperative CA 19-9 Levels Predict Overall Survival in Resected Pancreatic Adenocarcinoma". College of American Pathologists, Grapevine, Texas on September 1114, 2011
  2. Sabrina C. Wentz, Zhiguo Zhao, Yu Shyr, Fen Xia, Bapsi Chakravarthy, and M. Kay Washington. "Lymph Node Ratio, Total Node Count, and Preoperative CA 19-9 Levels Predict Overall Survival in Resected Pancreatic Adenocarcinoma". Archives of Pathology & Laboratory Medicine, September, 2011
  3. Stover DG, Cushman-Vokoun AM, Zhao Z, Koehler EA, Vnencak-Jones CL, Berlin J., et al., "Analysis of BRAF and KRAS mutations in colorectal cancer and rectal carcinogenesis via fluorescent allele-specific PCR". American Society of Clinical Oncology (ASCO) - Gastrointestinal Cancers Symposium. San Francisco, CA. Jan. 20-22, 2011.
  4. Tatsuki Koyama, Ph.D., Zhiguo Zhao M.S., Je rey D. Blume, Ph.D. Pitfalls of simplistic normalization in basic science experiments". Joint Statistical Meeting. Vancouver, BC, Canada. Jul. 29 - Aug. 5, 2010.
  5. Adam Esbenshade, MD, Richard Ho MD, Ayumi Shintani PhD, MPH, Zhiguo Zhao, MS, Debra L. Friedman, MD, MS. Dapsone Induced Methemoglobinemia: A Dose-Related Occurrence?". APPHO 23rd Annual Meeting. Montreal, Quebec, Canada. Apr. 7-10, 2010.
  6. K. Mukherjee, M. Hilmes, M. C. Shinall, Jr, K. J. Wilson, D. Ayers, A. Zhao, H. N. Lovvorn, III. "Image Analysis of Hepatoblastoma Decay during Induction Chemotherapy". J Surg Res 158(2):343-4 (2010); The 5th Annual Academic Surgical Congress. San Antonio, TX. Feb. 2010
  7. Tatsuki Koyama, Ph.D. and Zhiguo (Alex) Zhao, M.S.. Failed `Normalization': Dividing by the Control Average". Vanderbilt 2009 Cancer Epidemiology, Biostatistics, Bioinformatics Retreat. Vanderbilt University. Dec. 4, 2009
  8. William Wu, Joan Zhang, Ming Li, and Zhiguo (Alex) Zhao. What Makes VICC a Top Cancer Center? --- An analysis of data from U.S. News & World Report". Biostatistics Department Poster Contest. Vanderbilt University. Nov. 2008
  9. K. K. Ancell, Z. Zhao, Y. Shyr, J. Berlin. Patient satisfaction with placement of implantable venous access devices. Submitted for the 2011 ASCO Annual Meeting (June 3-7, 2011)

Presentations

Introduction to R Functionality with Illustrations, MS continuing education workshop, Department of Biostatistics, Vanderbilt University. January 20, 2011

Survival/Failure Time Analysis in Clinical Research, Clinical Research Center Research Skills Workshop, Vanderbilt University. October 29, 2010

What You See May Not be What You Get? --- A Brief Introduction to Over tting , Cancer Biostatistics Workshop, Vanderbilt Ingram Cancer Center. April 16, 2010

What causes the difference?, Cancer Biostatistics Division Meeting, Vanderbilt University. May 26, 2009

Continuing Education

  1. Absolute Risk Prediction. Half-day tutorial, Conference on Risk Assessment and Evaluation of Predictions, Silver Spring, MD. Dr. Mitchell H. Gail, Dr. Ruth Pfei er. Oct. 12 - Oct. 14, 2011
  2. Current Methods for Evaluating Prediction Performance of Biomarkers and Tests. Half-day tutorial, Conference on Risk Assessment and Evaluation of Predictions, Silver Spring, MD. Dr. Margaret S. Pepe. Oct. 12 - Oct. 14, 2011
  3. Compiling Programs. ACCRE, Vanderbilt University, Feb. 17 2011
  4. Job Scheduler Details. ACCRE, Vanderbilt University, Feb. 16 2011
  5. Introduction to the Compute Cluster. ACCRE, Vanderbilt University, Feb. 01 2011
  6. Introduction to Unix/Linux. ACCRE, Vanderbilt University, Jan. 31 2011
  7. Epidemiologic Theory and Methods II. Vanderbilt University, Jan. 2011 - May. 2011
  8. Epidemiologic Theory and Methods I. Vanderbilt University, Aug. 2010 - Dec. 2010
  9. NetCourse 101: Introduction to Stata. Six-week Online Course, StataCorp LP. Sep. 10 - Oct. 22, 2010
  10. Data Visualization using ggplot2. One-day Short Course, Vanderbilt University. Dr. Hadley Wickham. Jul. 27, 2010
  11. Eff ective Scientific Writing. Three Half-day Short Course, Vanderbilt University. Dr. Judith Swan. Jun. 15 & 16, 2010
  12. Regression Modeling Strategies. Five Half-day Short Course, Vanderbilt University. Dr. Frank Harrell. Feb. 2 - Feb 6, 2009
  13. Clinical Trials. Graduate Course (Audit only), MPH Program, School of Medicine, Vanderbilt University. Dr. Yu Shyr. Nov. 2008
  14. Cancer Biology. Graduate Course (Audit only), Department of Cancer Biology, Vanderbilt Ingram Cancer Center. Sep. 2008 - Nov. 2008

Services

  • Co-Chair: Staff Biostatistician Search committee. June 2011 - Present
  • Member: Staff Biostatistician Search committee. July 2008 - Present
  • Project Leader: Improving Public Relations Through The Flat Panel Screen Project. 2008 - Present
  • Project Leader: Improving the sample size justifi cation and statistical analysis plan for protocols and grant applications, Jan. 2011 - Present

Membership

American Statistical Association
International Biometric Society (ENAR)
Topic attachments
I Attachment Action Size Date Who Comment
CRC_Survival_10292010.pdfpdf CRC_Survival_10292010.pdf manage 536.1 K 29 Oct 2010 - 11:31 AlexZhao GCRC survival analysis
CV-zhiguo-short.pdfpdf CV-zhiguo-short.pdf manage 142.3 K 07 Nov 2011 - 13:19 AlexZhao Alex Zhao's CV, long version
Overfitting_0416_updated.pdfpdf Overfitting_0416_updated.pdf manage 451.5 K 16 Mar 2015 - 09:27 AlexZhao  
ProgramR.pdfpdf ProgramR.pdf manage 305.4 K 31 Jan 2011 - 21:42 AlexZhao Programming in R
Topic revision: r32 - 16 Apr 2015, YapingShi
 

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