Journal Club

Grants, IRB Proposals

1. Dr Peltier (8/09) Palliative care education grant.
2. Drs Boyd, Walters, Malow (8/09) Surgical Treatment of Obstructive Sleep Apnea by Maxillomandibular Advancement
3. Dr David Charles (7/09) Emotion recognition deficits in early stage Parkinson's Disease
4. Dr Art Walters (7/09) Study of Cerebrospinal Fluid Endogenous Opioids and Blood mRNA in Patients with Restless Legs Syndrome Versus Controls.
5. Dr David Charles (7/09) Progression of early Parkinson's disease after treatment with DBS, an extension of an ongoing pilot trial
6. Dr Ram Siriram (7/09) Regulation of p53 and p53 isoforms by beta interferon
7. Dr Art Walters (6/09) Circadian Rhythm of the Restless Legs Syndrome.
8. Dr David Charles (6/09) Spasticity prevalence and clinical impact in long term care residents, resubmission.
9. Dr David Charles (6/09) Inter-rater reliability of a spasticity diagnosis algorithm.
10. Dr Sriram (5/09) DNA damage pathway defects in MS.
11. Dr Art Walters (5/09) Magnetic Resonance Imaging study of patients with Restless Legs Syndrome versus controls: The search for silent strokes.
12. Dr Art Walters (2/09) Study of cerebrospinal fluid endogenous opioids in patients with Restless Legs Syndrome versus controls.
13. Dr David Charles (2/09) Spasticity prevalence and clinical impact in long term care residents.
14. Dr Scott Boyd (2/09) Surgical Treatment of OSA by Maxillomandibular Advancement.
15. Dr Chris Lee and Amanda Peltier (2/09) A study to look at repeated ultrasound measurements of muscle thickness over time.
16. Dr Arthur Walters (2/09) Study of cerebrospinal fluid endogenous opioids in patients with Restless Legs Syndrome versus controls
17. Dr Fenna Phibbs (1/09) GaitRite analysis of walking.
18. Dr Eliza Robertson and Peter Donofrio (1/09) Double crush syndrome study.
19. Dr Kanika Bagai (12/08) Variability of Fibrinolytic Markers and Endothelial Function in obese and non-obese patients with Obstructive Sleep Apnea.
20. Dr Amanda Peltier (9/08) Sleep-Disordered Breathing in Amyotrophic Lateral Sclerosis.
21. Dr David Charles (6/08 - 8/08) Deep brain stimulation for progression of Parkinson’s disease.
22. Dr Gregory Barnes (6/08) Relation of Sleep Epileptiform Activity to Insomnia and Daytime Behaviors in Children with Autism Spectrum Disorders.
23. Dr. David Charles (2/08) Retrospective analysis of PD progression after DBS using levodopa total daily dose as a surrogate disease marker.
24. Dr. David Charles (11/07) Retrospective Analysis of Cervical Dystonia Patient Population and Treatment Experience at Vanderbilt University.
25. Dr David Charles (9/07) Prevalence and treatment of spasticity in veterans with brain injuries living in long term care facilities.
26. Dr Siddharama Pawate (9/07)Detection of brain iron in multiple sclerosis.
27. Dr David Charles (8/07 ) DBS study. Data and safety monitoring reports.
28. Dr Amanda Peltier (6/07) Qualitative Approach to Skin Biopsy in Diabetic Neuropathy Using Immunolabeling for Nociceptive C Fiber Subclasses. Clustering analysis, GEE.
29. Dr Kanika Bagai (06/07) Variability of Fibrinolytic markers and Endothelial Function in Obstructive Sleep Apnea. Statistical analysis of circadian variations using mixed effects models.(Report)
30. Dr Pradumna Singh (03/07)Is There a Role for I.V. Levetiracetam in Controlling Acute Repetitive Seizures in the Epilepsy Monitoring Unit?
31. Dr David Charles (3/07) Botox for cervical pain study. Cross-over study.
32. Dr Sriram Subramaniam (2/07) A grant looking at correlations between immunochemistry values and MRI measures for mice.
33. Dr Amanda C. Peltier (2/07)Differences in Sympathetic Function Between African Americans and Caucasians.
34. Dr Kimberly Hutchison (2/07) Neural correlates of adaptation to sleep deprivation in obstructive sleep apnea - A Pilot Study. Database setup.
35. Dr Kanika Bagai (2/07 - 7/07)Variability of Fibrinolytic markers and Endothelial Function in Obstructive Sleep Apnea. Statistical modelling of circadian variation of biomarkers.
36. Dr Fenna Phibbs (2/07)A cross-over study looking at monopolar vs. biopolar stimulation on patients quality of life.
37. Dr Peter D. Donofrio (2/07)Theophylline and Respiratory Fatigue in Amyotrophic Lateral Sclerosis. A two-period crossover study.
38. Dr Kanika Bagai (10/06) Obstructive Sleep Apnea Syndrome and PAI-1.
39. Dr. Amanda C. Peltier (9/06)A grant to look at the specific percentages of nociceptive C fiber subclasses affected in different neuropathies to determine if this information could be used for diagnostic purposes.
40. Dr Mike Edgeworth (7/06) A PHASE I/II STUDY OF COMBINING SUNITINIB WITH TEMOZOLOMIDE AND RADIATION THERAPY IN NEWLY DIAGNOSED GLIOBLASTOMA MULTIFORME. Design of a cancer clinical trial.
41. Dr David Charles (5/06) Treatment for spasticity in Tenn.
42. Dr Michael K. Cooper (4/06) Association of Hedgehog pathway activity with brain tumors.
43. Dr Moneeb Ehtesham (3/06) Assistance with grant preparation. Wilcoxon test.
44. Drs Nabil J. Azar, Bassel Abou-Khalil (1/06 - 2/06)Seizure Interval Prolongation (SIP) effect after brief AED withdrawal.
45. Drs David Charles, Chris Kao (1/06 - 2/06)Electrical activity within STN and disease progression in PD.
46. Dr David Charles (1/06 ) Safety and Tolerability of Neurostimulation in Early State Parkinson’s Disease.
47. Drs Bassel Abou-Khalil, Pradumna Singh, Amir Arain (12/05)Effect of Educational and Social Services on Seizure Control and Quality of Life Outcome in Patients Presenting to the Emergency Room with Seizures. Design of quality of life studies in clinical trials.
48. Drs Gregory Barnes and Anup Patel (11/05) Levetiracetam induced suppression of Refractory Neonatal Seizures. Measuring change from baseline.

Manuscripts

1. Dr Amanda Peltier (11/09 - ) AUTONOMIC DYSFUNCTION IN OBSTRUCTIVE SLEEP APNEA - ROLE OF IMPAIRED GLUCOSE REGULATION.
2. Dr David Charles (9/09-) Retrospective analysis of PD progression after DBS using levodopa total daily dose as a surrogate disease marker (Report)
3. Dr Kim Hutchison (9/09-) Neural correlates of adaptation to sleep deprivation in obstructive sleep apnea - A Pilot Study (Report)
4. Drs Nabil J. Azar, Bassel Abou-Khalil (6/09-) Discriminating Features of Convulsive Epileptic and Non-epileptic Seizures.
5. Dr Amanda Peltier (2/09 - ) QUANTITATIVE SUDOMOTOR AXON REFLEX TEST AND UTAH EARLY NEUROPATHY SCALE IN HIV INFECTION. (Report)
6. Dr Salman Zubair (9/08-) UTILITY OF 2HR VIDEOEEG MONITORING COMPARED TO ROUTINE EEG.
7. Dr Siddharama Pawate (9/08 -12/08, 11/09-) Deep gray matter T2 hypointensity in multiple sclerosis and other neurological diseases: a 3T MRI study.
8. Drs Nabil J. Azar, Bassel Abou-Khalil (2/08 - )Seizure Interval Prolongation (SIP) effect after brief AED withdrawal. (Report)
9. Dr Amanda Peltier (8/07 - 11/07, 1/09)Distal Sudomotor Abnormalities in Postural Tachycardla Syndrome. (Report)
10. Dr Davit Mrelashvili (6/07 - 3/08)Pregabalin Efficacy and Tolerability in Patients with Intractable Partial Seizures A Post-Marketing Analysis.
11. Dr Siddharama Pawate (8/07 - 10/07)Mycophenolate moefetil in Multiple Sclerosis.
12. Dr Nabil Azar (8/07)Oxcarbazepine withdrawal seizures during epilepsy monitoring. Poisson regression with repeated measures, survival analysis.
13. Dr Mengesha, Dr Abou-Khalil (08/07)Visual Field Defects after Selective Amygdalohippocampectomy and Standard Temporal Lobectomy. Generalized estimating equations for repeated measures.
14. Dr Kanika Bagai (03/07 - 11/07, 1/09)The Neglected Spectrum of REM Obstructive Sleep Apnea.
15. Dr Kanika Bagai (10/06 - 7/07) Electrophysiological Patterns of Diabetic Polyneuropathy. Poisson model with repeated measures.
16. Dr Amanda Peltier (10/06 - 11/07)Reliability and Sensitivity of Electrophysiology Studies in a Clinical Trial of Early Neuropathy Associated with Impaired Glucose Regulation. Intraclass correlations.
17. Drs Nabil Azar, Aubrey Wright, Bassel Abou-Khalil (10/06 - 2/07)Generalized Tonic-Clonic Seizures after Acute Oxcarbazepine Withdrawal.
18. Drs Nabil Azar, Tania F Tayah and others (10/06 -1/07 )Value of post-ictal breathing pattern in differentiation of generalized tonic-clonic seizures, non-epileptic convulsive seizures and hypermotor frontal seizures. Logistic prediction model.
19. Dr Kimberly Hutchison (7/06 - 5/07 ) First night effect in hospital and hotel-based laboratory.
20. Dr Sriram Subramaniam (2/06 - )Gene expression profiling for multiple sclerosis. Analysis of microarray data with Bioconductor software.
21. Dr Amanda C. Peltier (1/06 - 3/06)Autonomic Dysfunction in Obstructive Sleep Apnea Is Associated with Impaired Glucose. Analysis of results.

Consultations and Short Data Analysis

1. Dr Nabil J Azar (11/09) Non-diagnostic initial long-term video-EEG study, and yield of repeat studies.
2. Dr Martin Gallagher (11/09) Consultations on multiple group KS test.
3. Dr Kanika Bagai (7/09) Variability in Endothelial Function and Fibrinolytic balance in OSA
4. Dr. Amir Arain (5/09) Pseudoseizure communication study.
5. Dr. Amir Arain (5/09) Epilepsy Monitoring satisfaction survey.
6. Dr Fanglin Zhang (Sriram Lab) (5/09) Pathway analysis of microarray datasets. (Report)
7. Dr David Charles and Elyne Kahn (3/09) DEEP BRAIN STIMULATION: ITS EFFECT ON RATE OF INCREASE OF ANTIPARKINSONIAN MEDICATION.
8. Dr Amanda Peltier (4/09) Prevention of peripheral neuropathy by treating metabolic syndromes in HIV patients.
9. Dr Fanglin Zhang,Subramaniam Sriram (2/09) Discussion on a microarray study with repeated measures.
10. Drs Lisa Hermann, Kirshner Howard (12/08) External Ventricular Drain in stroke treatment.
11. Dr Christopher Nolte (11/08) Discussions on analysis of CPAP (continuous positive airway pressure) machine use.
12. Dr Kevin Haas (11/08) Dose response study for Mice with Angelman syndrome. (Report)
13. Dr Christopher Lee (11/08) Brief consultation on repeated measures analysis.
14. Dr Vishal Jani (10/08) MESA study discussions.
15. Dr Mostafa Hammoudi (9/08) Discussion on an EEG study.
16. Dr Chris Kao (9/08) Discussion of a paper.
17. Dr Subramaniam Sriram (9/08) Efficacy of DFP to reduce Fe in dentate nuclei: MRI metrics of efficacy.
18. Dr Arain Amir (8/08 - 12/08) Analysis of Hospital Discharge Database
19. Dr Liya Beyderman (7/08) Analysis of statistics related to consultations at Vanderbilt Adult Neurology clinic.
20. Dr Bassel Abou-khalil (7/08) The association of temporal tip epilepsy and hypermotor seizures.
21. Dr Christopher Michael (6/08) Literacy/numeracy testing between adherent and non-adherent CPAP patients.
22. Dr.Pradumna Singh, Dr. Nandakumar Bangalore (5/08) Does intravenous levetiracetam have a role in the management of acute repetitive seizures?
23. Dr. Nabil Azar, Dr.Bassel Abou-Khalil (5/08) Seizure interval prolongation (SIP) after brief AED withdrawal- experience with new AEDs.
24. Dr.Amir Arain (5/08) DIAGNOSTIC YIELD OF REGULAR EEG VERSUS 2 HRS LONG TERM OUTPATIENT VIDEO EEG MONITORING.
25. Dr. Amir Arain (5/08) Racial disparity in Patients Admitted to Hospitals in Tennessee for Epilepsy and Seizures .
26. Dr. Amir Arain (5/08) Psychopathology and Family Dynamics in Patients with Psychogenic Non-Epileptic Spells (PNES).
27. Dr Kevin Ess (5/08) Survival Analysis of Rapamycin treated CKO mice.
28. Dr Siddharama Pawate (4/08) Mycophenolate Mofetil in the Treatment of Multiple Sclerosis. Poster.
29. Neil Manus (11/07-2/08) Retrospective CD project.
30. Dr. Nandakumar Bangalore Vittal (12/07) Sample size calculations for a research proposal.
31. Dr. Martin J. Gallagher (12/07) Stats question.
32. Drs Gregory Barnes and John Flatt (10/07) Sample size calculations for a clincal trial.
33. Dr Suzanne Goldman (10/07) Stats questions and data management for Williams Syndrome study.
34. Dr Siddharama Pawate (10/07) Mycophenolate Mofetil in the treatment of Multiple Sclerosis. (Abstract for conference)
35. Dr Andrea Lagrange (6/07)The effect of RNA editing to modify GABA-A receptor properties.
36. Dr David Charles (5/07)The therapeutic use of botulinum toxin type A in treating neck and upper back pain of muscular origin: a pilot study.
37. Dr. Mengesha, Theodros (6/07) Quantitative Analysis of Visual Field Defects after Selective Amygdalohippocampectomy and Standard Temporal Lobectomy. Data analysis.
38. Dr Alwan, Ahmad (5/07) Clinical and electrophysiologic characterization of seizures occurring in waking versus sleep. Data collection and analysis.
39. Dr David Charles (2/07 ) Safety and Tolerability of Neurostimulation in Early State Parkinson’s Disease. Data Monitoring Committee report.
40. Dr Pradumna P Singh et al. (11/06 -) The Characteristics of Patients Visiting Emergency Room Repeatedly for Seizures.
41. Dr. Amanda C. Peltier (9/06)Discussion on a retrospective case-control study.
42. Dr Greg Barnes (9/06)Risk factors for developing post-neonatal epilepsy. Suggestions on revision of manuscript.
43. Dr. Tom Davis (7/06) Discussion on crossover study.
44. Dr Ajay Shukla (7/06) Significance of median motor nerve latency and amplitude in deciding the surgical treatment of CTS. Discussion on manuscipt writing.
45. Dr. BethAnn McLaughlin (7/06) Evaluating the changes in mitochondrial membrane potential induced by isoprostanes under normal and hypoxic conditions.Calculation and estimation of statistical parameters.
46. Dr Kimberly Hutchison (5/06) Neural correlates of adaptation to sleep deprivation in obstructive sleep apnea - A Pilot Study.
47. Courtney Schadt (3/06)Reduction of medical costs after DBS surgury.(Abstract)
48. Drs Fenna Phibbs and John Fang (3/06) Manganese, Movement Disorders, and Welding. Sample size calculation.
49. Dr Andre Lagrange (3/06) Database questions.
50. Dr Sriram, Subramaniam (2/06) Discussion of paper on Meta-Analysis.
51. Dr Michael K. Cooper (2/06) Analysis of Hedgehog pathway activity in brain tumors. Assistance with manuscript preparation.
52. Drs Annette Chihorek, Beth Malow (2/06) Obstructive sleep apnea in older adults with epilepsy.
53. Dr David Charles (1/06) Prevalence of spasticity in adults with mental retardation. Sample size calculation.
54. Dr Fenna Phibbs (1/06)Analysis of a multivariate crossover study.