Biostatistics Weekly Seminar

Some New Developments for Neuroimaging Inference Using the PBJ R Package

Simon Vandekar, PhD
Vanderbilt University Medical Center

Spatial extent inference (SEI) is widely used across neuroimaging modalities to study brain-behavior associations that inform our understanding of disease. Recent studies have shown that Gaussian random field (GRF) based tools can have hugely inflated family-wise error rates (FWERs). We developed a semiparametric bootstrap joint (sPBJ) testing procedure to address the limitations of available methods; our approach is the image equivalent of a robust sandwich covariance estimator and yields consistent estimates of standard errors, even under model misspecification.

Zoom (Link to Follow)
02 September 2020

Topic revision: r1 - 26 Aug 2020, AndrewSpieker

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