Difference: GuanhuaChen (1 vs. 29)

Revision 29
22 Oct 2017 - Main.GuanhuaChen
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META TOPICPARENT name="WikiUsers"

Guanhua (Josh) Chen, PhD

Assistant Professor

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Department of Biostatistics and Medical Informatics

University of Wisconsin-Madison

 

email: gchen25@wisc.edu




Research Interests

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  • Semiparametric Methods
  • Survival Analysis
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Curriculum Vitae

CV (last updated Aug 2014)

Vanderbilt Collaborations

  • Biomedical Informatics

Published Papers

  • Methodology
  1. Bush WS, Chen G, Torstenson ES and Ritchie MD: LD-Spline: LD-Spline: Mapping SNPs on genotyping platforms to genomic regions using patterns of linkage disequilibrium, BioData Mining, 2009, 2:2-7
  2. Chen G, Sullivan PF, Kosorok MR: Biclustering with heterogenous variance. Proceedings of the National Academy of Sciences, 2013, 110(30): 12253-12258. Code: HSSVD
  3. Chen G, Liu Y, Shen D, Kosorok MR: Composite large margin classifiers with latent subclasses. Statistical Analysis and Data Mining, 2016, 9(2): 75-88.
  4. Chen G, Zeng D, Kosorok MR: Personalized dose finding using outcome weighted learning (with discussion). Journal of the American Statistical Association, 2016, in press.
  5. Tang ZZ^, Chen G^, Alekseyenko A: Hypothesis Testing for Microbiome Profile. (^ for equal contribution and corresponding authors) Bionformatics, 2016, 32(17): 2618-2625.
  6. Zhu R, Zhao YQ, Chen G, Ma S, Zhao H: Greedy Tree Learning of Optimal Personalized Treatment Rules. Biometrics, 2016, in press.
  7. Tang ZZ, Chen G, Alekseyenko A, Li H: A general framework for association analysis of microbial community on a taxonomic tree. Bionformatics, 2016, in press.
  • Collaborative
  1. Bloom RJ, Kahler AK, Collins AL, Chen G, Cannon TD, Hultman C, Sullivan PF: Comprehensive analysis of copy number variation in monozygotic twins discordant for bipolar disorder or schizophrenia. Schizophrenia Research, 2013, 146(1-3):289-290.
  2. Wright FA, Sullivan PF, ... , Chen G , ... , Boomsma DI: Heritability and genomics of gene expression in peripheral blood. Nature Genetics, 2014, 46:430-437.
  3. Szatkiewicz J, O'Dushlaine CT, Chen G , Sullivan PF: Copy number variation in Schizophrenia in Sweden. Molecular Psychiatry, 2014, 19:762-773
  4. Jhamb M, Cavanaugh K, Bian A, Chen G , Ikizler TA, Unruh ML, Abdel-Kader K: Disparities in Electronic Health Record Patient Portal Use in Nephrology Clinics: Correlates and Outcomes. Clinical Journal of the American Society of Nephrology, 2015, 10(11): 2013-2022.
  5. Deger SM, Huang AM, Ellis CD, Booker C, Bian A, Chen G, Abumrad NN, Ikizler TA: High Dose Omega-3 Fatty Acids Attenuate Skeletal Muscle Protein Breakdown in Maintenance Hemodialysis Patients. Clinical Journal of the American Society of Nephrology , 2016, 11(7): 1227-1235.
  6. Leaf, DE, Christov M, Jupner H, Siew E, Ikizler TA, Bian A, Chen G, Sabbisetti VS, Bonventre JV, Wolf M, Waikar SS: FGF23 and Cardiac Surgery-Associated Acute Kidney Injury. Kidney International , 2016, 89(4):939-948.
  7. Denny GB, Deger SM, Chen G, Bian A, Feng S, Booker CA, Kesler JT, David S, Ellis CD, Ikizler TA: Leucine disposal rate for assessment of amino acid metabolism in maintenance hemodialysis patients. BMC Nutrition, 2016, 2(1): 31.
  8. Kensinger C, Bian A, Fairchild M, Chen G, Lipworth-Elliot L, Ikizler TA, Birdwell KA: Long term evolution of endothelial function during kidney transplantation. BMC Nephrology, 2016, 17(1): 160.
  9. Kensinger C, Hernandez A, Bian A, Fairchild M, Chen G, Lipworth-Elliot L, Ikizler TA, Birdwell KA: Longitudinal Assessment of Cardiac Morphology and Function Following Kidney Transplantation. accepted in Clinical Transplantation, 2016.

Technical report

  1. Liu Q, Chen G, Kosorok MR, Bair E: Biclustering Via Sparse Clustering. arxiv:1407.3010
  2. Zhu R, Zhao YQ, Chen G: Stabilized Dynamic Treatment Regime.
  3. Chen G: Variable screening for classification with measurement error in the class label.

Software/Code

HSSVD: R package that performs biclustering, which allows heterogeneous variance.

Useful Links

EPP for ACCRE; Statistics Plan Goals
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Personal Preferences (details in Macros) 
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  • Set ALLOWTOPICCHANGE = GuanhuaChen
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    • Set RELEASEEDITLOCKCHECKBOX = checked="checked"
Related topics -->

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META FILEATTACHMENT attachment="cv_chen.pdf" attr="" comment="" date="1407531987" name="cv_chen.pdf" path="cv_chen.pdf" size="125597" user="GuanhuaChen" version="1"
META FILEATTACHMENT attachment="image.png" attr="" comment="" date="1407540488" name="image.png" path="image.png" size="110021" user="GuanhuaChen" version="1"
Revision 28
13 Sep 2017 - Main.GuanhuaChen
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META TOPICPARENT name="WikiUsers"

Guanhua (Josh) Chen, PhD

Assistant Professor

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E-mail: g dot chen at vanderbilt.edu
Phone: 615-343-3624
Fax: 615-343-4924
Office: 2525 West End, 11128A
Vanderbilt University School of Medicine
Department of Biostatistics
2525 West End, Suite 11000
Nashville, TN 37203
>
>

email: gchen25@wisc.edu




 

Research Interests

  • Statistical Learning/ Machine Learning
Revision 27
12 Dec 2016 - Main.GuanhuaChen
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META TOPICPARENT name="WikiUsers"
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  • Methodology
  1. Bush WS, Chen G, Torstenson ES and Ritchie MD: LD-Spline: LD-Spline: Mapping SNPs on genotyping platforms to genomic regions using patterns of linkage disequilibrium, BioData Mining, 2009, 2:2-7
  2. Chen G, Sullivan PF, Kosorok MR: Biclustering with heterogenous variance. Proceedings of the National Academy of Sciences, 2013, 110(30): 12253-12258. Code: HSSVD
Changed:
<
<
  1. Chen G, Liu Y, Shen D, Kosorok MR: Composite large margin classifiers with latent subclasses. Statistical Analysis and Data Mining, 2016, in press.
  2. Chen G, Zeng D, Kosorok MR: Personalized dose finding using outcome weighted learning. Journal of the American Statistical Association, 2016, in press.
  3. Tang ZZ^, Chen G^, Alekseyenko A: Hypothesis Testing for Microbiome Profile. (^ for equal contribution and corresponding authors) Bionformatics, 2016, in press.
  4. Zhu R, Zhao YQ, Chen G, Ma S, Zhao H: Greedy Tree Learning of Optimal Personalized Treatment Rules. Biometrics, 2016, tentatively accepted.
>
>
  1. Chen G, Liu Y, Shen D, Kosorok MR: Composite large margin classifiers with latent subclasses. Statistical Analysis and Data Mining, 2016, 9(2): 75-88.
  2. Chen G, Zeng D, Kosorok MR: Personalized dose finding using outcome weighted learning (with discussion). Journal of the American Statistical Association, 2016, in press.
  3. Tang ZZ^, Chen G^, Alekseyenko A: Hypothesis Testing for Microbiome Profile. (^ for equal contribution and corresponding authors) Bionformatics, 2016, 32(17): 2618-2625.
  4. Zhu R, Zhao YQ, Chen G, Ma S, Zhao H: Greedy Tree Learning of Optimal Personalized Treatment Rules. Biometrics, 2016, in press.
  5. Tang ZZ, Chen G, Alekseyenko A, Li H: A general framework for association analysis of microbial community on a taxonomic tree. Bionformatics, 2016, in press.
 
  • Collaborative
  1. Bloom RJ, Kahler AK, Collins AL, Chen G, Cannon TD, Hultman C, Sullivan PF: Comprehensive analysis of copy number variation in monozygotic twins discordant for bipolar disorder or schizophrenia. Schizophrenia Research, 2013, 146(1-3):289-290.
  2. Wright FA, Sullivan PF, ... , Chen G , ... , Boomsma DI: Heritability and genomics of gene expression in peripheral blood. Nature Genetics, 2014, 46:430-437.
  3. Szatkiewicz J, O'Dushlaine CT, Chen G , Sullivan PF: Copy number variation in Schizophrenia in Sweden. Molecular Psychiatry, 2014, 19:762-773
  4. Jhamb M, Cavanaugh K, Bian A, Chen G , Ikizler TA, Unruh ML, Abdel-Kader K: Disparities in Electronic Health Record Patient Portal Use in Nephrology Clinics: Correlates and Outcomes. Clinical Journal of the American Society of Nephrology, 2015, 10(11): 2013-2022.
Changed:
<
<
  1. Deger SM, Huang AM, Ellis CD, Booker C, Bian A, Chen G, Abumrad NN, Ikizler TA: High Dose Omega-3 Fatty Acids Attenuate Skeletal Muscle Protein Breakdown in Maintenance Hemodialysis Patients. Clinical Journal of the American Society of Nephrology , 2016, in press.
  2. Leaf, DE, Christov M, Jupner H, Siew E, Ikizler TA, Bian A, Chen G, Sabbisetti VS, Bonventre JV, Wolf M, Waikar SS: FGF23 and Cardiac Surgery-Associated Acute Kidney Injury. Kidney International , 2016, in press.
>
>
  1. Deger SM, Huang AM, Ellis CD, Booker C, Bian A, Chen G, Abumrad NN, Ikizler TA: High Dose Omega-3 Fatty Acids Attenuate Skeletal Muscle Protein Breakdown in Maintenance Hemodialysis Patients. Clinical Journal of the American Society of Nephrology , 2016, 11(7): 1227-1235.
  2. Leaf, DE, Christov M, Jupner H, Siew E, Ikizler TA, Bian A, Chen G, Sabbisetti VS, Bonventre JV, Wolf M, Waikar SS: FGF23 and Cardiac Surgery-Associated Acute Kidney Injury. Kidney International , 2016, 89(4):939-948.
  3. Denny GB, Deger SM, Chen G, Bian A, Feng S, Booker CA, Kesler JT, David S, Ellis CD, Ikizler TA: Leucine disposal rate for assessment of amino acid metabolism in maintenance hemodialysis patients. BMC Nutrition, 2016, 2(1): 31.
  4. Kensinger C, Bian A, Fairchild M, Chen G, Lipworth-Elliot L, Ikizler TA, Birdwell KA: Long term evolution of endothelial function during kidney transplantation. BMC Nephrology, 2016, 17(1): 160.
  5. Kensinger C, Hernandez A, Bian A, Fairchild M, Chen G, Lipworth-Elliot L, Ikizler TA, Birdwell KA: Longitudinal Assessment of Cardiac Morphology and Function Following Kidney Transplantation. accepted in Clinical Transplantation, 2016.
 

Technical report

  1. Liu Q, Chen G, Kosorok MR, Bair E: Biclustering Via Sparse Clustering. arxiv:1407.3010
Revision 26
11 Jul 2016 - Main.GuanhuaChen
Line: 1 to 1
 
META TOPICPARENT name="WikiUsers"
Line: 39 to 39
 

Technical report

  1. Liu Q, Chen G, Kosorok MR, Bair E: Biclustering Via Sparse Clustering. arxiv:1407.3010
  2. Zhu R, Zhao YQ, Chen G: Stabilized Dynamic Treatment Regime.
Changed:
<
<
  1. Chen G: Variable screening for classification with measurement errro in the class label.
>
>
  1. Chen G: Variable screening for classification with measurement error in the class label.
 

Software/Code

HSSVD: R package that performs biclustering, which allows heterogeneous variance.
Revision 25
08 Jul 2016 - Main.GuanhuaChen
Line: 1 to 1
 
META TOPICPARENT name="WikiUsers"
Line: 27 to 27
 
  1. Chen G, Liu Y, Shen D, Kosorok MR: Composite large margin classifiers with latent subclasses. Statistical Analysis and Data Mining, 2016, in press.
  2. Chen G, Zeng D, Kosorok MR: Personalized dose finding using outcome weighted learning. Journal of the American Statistical Association, 2016, in press.
  3. Tang ZZ^, Chen G^, Alekseyenko A: Hypothesis Testing for Microbiome Profile. (^ for equal contribution and corresponding authors) Bionformatics, 2016, in press.
Added:
>
>
  1. Zhu R, Zhao YQ, Chen G, Ma S, Zhao H: Greedy Tree Learning of Optimal Personalized Treatment Rules. Biometrics, 2016, tentatively accepted.
 
  • Collaborative
  1. Bloom RJ, Kahler AK, Collins AL, Chen G, Cannon TD, Hultman C, Sullivan PF: Comprehensive analysis of copy number variation in monozygotic twins discordant for bipolar disorder or schizophrenia. Schizophrenia Research, 2013, 146(1-3):289-290.
  2. Wright FA, Sullivan PF, ... , Chen G , ... , Boomsma DI: Heritability and genomics of gene expression in peripheral blood. Nature Genetics, 2014, 46:430-437.
Line: 37 to 38
 

Technical report

  1. Liu Q, Chen G, Kosorok MR, Bair E: Biclustering Via Sparse Clustering. arxiv:1407.3010
Deleted:
<
<
  1. Zhu R, Zhao YQ, Chen G, Ma S, Zhao H: Greedy Tree Learning of Optimal Personalized Treatment Rules.

 
  1. Zhu R, Zhao YQ, Chen G: Stabilized Dynamic Treatment Regime.
Added:
>
>
  1. Chen G: Variable screening for classification with measurement errro in the class label.
 

Software/Code

HSSVD: R package that performs biclustering, which allows heterogeneous variance.
Revision 24
05 Jul 2016 - Main.GuanhuaChen
Line: 1 to 1
 
META TOPICPARENT name="WikiUsers"
Line: 26 to 26
 
  1. Chen G, Sullivan PF, Kosorok MR: Biclustering with heterogenous variance. Proceedings of the National Academy of Sciences, 2013, 110(30): 12253-12258. Code: HSSVD
  2. Chen G, Liu Y, Shen D, Kosorok MR: Composite large margin classifiers with latent subclasses. Statistical Analysis and Data Mining, 2016, in press.
  3. Chen G, Zeng D, Kosorok MR: Personalized dose finding using outcome weighted learning. Journal of the American Statistical Association, 2016, in press.
Added:
>
>
  1. Tang ZZ^, Chen G^, Alekseyenko A: Hypothesis Testing for Microbiome Profile. (^ for equal contribution and corresponding authors) Bionformatics, 2016, in press.
 
  • Collaborative
  1. Bloom RJ, Kahler AK, Collins AL, Chen G, Cannon TD, Hultman C, Sullivan PF: Comprehensive analysis of copy number variation in monozygotic twins discordant for bipolar disorder or schizophrenia. Schizophrenia Research, 2013, 146(1-3):289-290.
  2. Wright FA, Sullivan PF, ... , Chen G , ... , Boomsma DI: Heritability and genomics of gene expression in peripheral blood. Nature Genetics, 2014, 46:430-437.
  3. Szatkiewicz J, O'Dushlaine CT, Chen G , Sullivan PF: Copy number variation in Schizophrenia in Sweden. Molecular Psychiatry, 2014, 19:762-773
  4. Jhamb M, Cavanaugh K, Bian A, Chen G , Ikizler TA, Unruh ML, Abdel-Kader K: Disparities in Electronic Health Record Patient Portal Use in Nephrology Clinics: Correlates and Outcomes. Clinical Journal of the American Society of Nephrology, 2015, 10(11): 2013-2022.
Changed:
<
<
  1. Deger SM, Huang AM, Ellis CD, Booker C, Bian A, Chen G, Abumrad NN, Ikizler TA: High Dose Omega-3 Fatty Acids Attenuate Skeletal Muscle Protein Breakdown in Maintenance Hemodialysis Patients. accepted in Clinical Journal of the American Society of Nephrology.
>
>
  1. Deger SM, Huang AM, Ellis CD, Booker C, Bian A, Chen G, Abumrad NN, Ikizler TA: High Dose Omega-3 Fatty Acids Attenuate Skeletal Muscle Protein Breakdown in Maintenance Hemodialysis Patients. Clinical Journal of the American Society of Nephrology , 2016, in press.
 
  1. Leaf, DE, Christov M, Jupner H, Siew E, Ikizler TA, Bian A, Chen G, Sabbisetti VS, Bonventre JV, Wolf M, Waikar SS: FGF23 and Cardiac Surgery-Associated Acute Kidney Injury. _Kidney International _, 2016, in press.

Technical report

  1. Liu Q, Chen G, Kosorok MR, Bair E: Biclustering Via Sparse Clustering. arxiv:1407.3010
  2. Zhu R, Zhao YQ, Chen G, Ma S, Zhao H: Greedy Tree Learning of Optimal Personalized Treatment Rules.
Changed:
<
<
  1. Tang ZZ^, Chen G^, Alekseyenko A: Hypothesis Testing for Microbiome Profile. (^ for equal contribution and corresponding authors)
>
>

 
  1. Zhu R, Zhao YQ, Chen G: Stabilized Dynamic Treatment Regime.

Software/Code

Line: 46 to 47
 

Useful Links

EPP for ACCRE; Statistics Plan
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Goals
 

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Revision 6
08 Aug 2014 - Main.GuanhuaChen
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META TOPICPARENT name="WikiUsers"
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Guanhua Chen, PhD

>
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Guanhua (Josh) Chen, PhD

 

Assistant Professor

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E-mail: g.chen@vanderbilt.edu
Phone: 615-343-3624
Fax: 615-343-4924
Office: 2525 West End, 11128A
Vanderbilt University School of Medicine
Department of Biostatistics
2525 West End, Suite 11000
Nashville, TN 37203
>
>
E-mail: g.chen@vanderbilt.edu
Phone: 615-343-3624
Fax: 615-343-4924
Office: 2525 West End, 11128A
Vanderbilt University School of Medicine
Department of Biostatistics
2525 West End, Suite 11000
Nashville, TN 37203
 

Research Interests

  • Statistical Learning/ Machine Learning
Revision 5
08 Aug 2014 - Main.GuanhuaChen
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META TOPICPARENT name="WikiUsers"
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GuanhuaChen

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Changed:
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Guanhua Chen, DrPH

>
>

Guanhua Chen, PhD

Assistant Professor

E-mail: g.chen@vanderbilt.edu
Phone: 615-343-3624
Fax: 615-343-4924
Office: 2525 West End, 11128A
Vanderbilt University School of Medicine
Department of Biostatistics
2525 West End, Suite 11000
Nashville, TN 37203
 
Changed:
<
<
Vanderbilt University School of Medicine
Department of Biostatistics
2525 West End Avenue, Suite 11000
Nashville, TN  37203-1738
james.c.slaughter at vanderbilt.edu

Phone: 615.322.0439
>
>

Research Interests

  • Statistical Learning/ Machine Learning
  • Personalized Medicine
  • High Dimensional Medical Records/Genetic Data
  • Semiparametric Methods
  • Survival Analysis
 
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ChrisSlaughter.JPG
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Curriculum Vitae

 
Changed:
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Research Interests

  • Longitudinal data analysis for observational studies
  • Latent variable methods
  • Bayesian statistics
  • Reproductive health applications

Education

  • DrPH in Biostatistics 2007
  • University of North Carolina at Chapel Hill
  • Dissertation: Bayesian Latent Variable Methods for Fetal Growth and Development
  • Advisor: Amy H Herring

  • MS in Biostatistics 2000
  • University of Washington
  • Advisor: Thomas Lumley

  • BS in Cell and Molecular Biology 1998
  • BS in Mathematics 1998
  • Tulane University

Work Experience

  • Assistant Professor 2007-Present
  • Vanderbilt University, Department of Biostatistics

  • Research Scientist 2000-2002
  • UW-EPA NW Research Center for Particulate Matter and Health

Courses Taught

>
>
CV (last updated Aug 2014)
 

Vanderbilt Collaborations

Changed:
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  • Gastroenterology
  • Neonatology
  • Vaccine Center
>
>
  • Biomedical Informatics
  • Nephrology
 

Published Papers

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  1. Vucovich M, Cotton R, Shelton E, Goettel J, Ehinger N, Poole S, Brown N, Wynn J, Paria B, Slaughter JC, Clark R, Rojas M, Reese J (2014). Aminoglycside-mediated relaxation of the ductus arteriosus in sepsis-associated PDA. American Journal of Physiology - Heart and Circulatory Physiology. Accepted. PMID: 24993047
  2. Chorna O, Solomon JE, Slaughter JC, Stark AR, Maitre NL. Abnormal sensory reactivity in preterm infants during the first year correlates with adverse neurodevelopmental outcomes at 2 years of age (2014). Archives of Disease in Childhood. 2014 Jul 22[ Epub ahead of print]. PMID: 25053637
  3. Maitre NL, Slaughter JC, Aschner JL, Key AP (2014). Hemisphere Differences in Speech-Sound Event-Related Potentials in Intensive Care Neonates: Associations and Predictive Value for Development in Infancy. Journal of Child Neurology. 2013 Jul 17. [Epub ahead of print]. PMID: 23864588
  4. Stouch AN, Zaynagetdinov R, Barham WJ, Stinnett AM, Slaughter JC, Yull FE, Hoffman HM, Blackwell TS, Prince LS. IKK-beta Activity Drives Fetal Lung Macrophage Maturation Along a Non-M1/M2 Paradigm. The Journal of Immunology (2014) Aug 1;193(3):1184-93. PMID 24981452.
  5. Maitre N, Henderson G, Gogliotti S, Pearson J, Simmons A, Wang L, Slaughter JC, Key, A. Feasibility of ERP methodology to evaluate changes in cortical processing after rehabilitation in children with cerebral palsy: a pilot study. Journal of Clinical and Experimental Neuropsychology 2014 Jun 23:1-11. PMID: 24953907
  6. Romano-Keeler J, Moore DJ, Wang C, Brucker RM, Fonnesbeck C, Slaughter JC, Li H, Curran DP, Meng S, Correa H, Lovvorn HN 3rd, Tang YW, Bordenstein S, George AL Jr, Weitkamp JH. (2014). Early life establishment of site-specific microbial communities in the gut.. Gut Microbes. 2014 Mar 1;5(2):192-201. doi: 10.4161/gmic.28442. PMID: 24637795.
  7. Maitre NL, Slaughter JC, Stark AR, Aschner JL, Anderson AW (2014). Validation of a brain MRI relaxometry protocol to measure effects of preterm birth at a flexible postnatal age. BMC Pediatrics. 14:84. doi:10.1186/1471-2431-14-84. PMID: 24678975
  8. Bates JT, Keefer C, Slaughter JC, Kulp D, Schief W, Crowe JE (2014) Escape from neutralization by the respiratory syncytial virus-specific neutralizing monoclonal antibody palivizumab is driven by changes in on-rate of binding to the fusion protein. Virology. 2014 Apr;454-455:139-44. PMID: 24725940
  9. Chorna O, Slaughter JC, Wang L, Stark A, Maitre, NL (2014). A Pacifier-Activated Music Player with motherís voice improves oral feeding in preterm infants Pediatrics. 2014 Mar;133(3):462-8. PMID: 24534413.
  10. Coburn LA, Horst SN, Chaturvedi R, Brown CT , Allaman MM, Scull BP, Singh K, Piazuelo MB, Chitnavis MV, Hodges ME, Rosen MJ, Williams CM, Slaughter JC, Beaulieu DB, Schwartz DA, Wilson KT (2013). High-throughput multi-analyte Luminex profiling implicates eotaxin-1 in ulcerative colitis. PLOS ONE. 2013 Dec 18;8(12):e82300. PMID: 24367513
  11. Casner M, Hoesli SJ, Slaughter JC, Hill M, Weitkamp JH (2014). Incidence of Catheter Related Bloodstream Infections in Neonates Following Removal of Peripherally Inserted Central Venous Catheters. Pediatric Critical Care Medicine. 2014 Jan;15(1):42-8. doi: 10.1097/PCC.0b013e31829f5feb. PMID: 24141656
  12. Yachimski P, Shi C, Slaughter JC, Washington MK (2013). Endoscopic mucosal resection of Barrett's esophagus detects high prevalence of subsquamous intestinal metaplasia. World Journal of Gastrointestinal Endoscopy. 2013 Dec 16;5(12):590-4. PMID: 24368934
  13. Coggins SA, Wynn JL, Hill ML, Slaughter JC, Ozdas-Weitkamp A, Jalloh O, Waitman LR, Carnevale RJ, Weitkamp JH (2013). Use of a computerized C-reactive protein (CRP) based sepsis evaluation in very low birth weight (VLBW) infants: A five-year experience. PLOS ONE. 2013 Nov 11;8(11):e78602. PMID: 24244325.
  14. Maitre NL, Smolinsky C, Slaughter JC, Stark AR. (2013). Adverse neurodevelopmental outcomes after exposure to phenobarbital and levetiracetam for the treatment of neonatal seizures. Journal of Perinatology. 2013 Nov;33(11):841-6. PMID: 24051577
  15. Matire NL, Slaughter JC, Aschner JL (2013). Early prediction of cerebral palsy after neonatal intensive care using motor development trajectories in infancy. Early Human Development. 2013 Oct;89(10):781-6. PMID: 23856349
  16. Gillam-Krakauer M, Cochran CM, Slaughter JC, Polavarapu S, McElroy SJ, Hernanz-Schulman M, Engelhardt B (2013). Correlation of abdominal rSO(2) with superior mesenteric artery velocities in preterm infants. Journal of Perinatology. 2013 Aug;33(8):609-12. PMID: 23392317.
  17. Cassani L, Sumner E, Slaughter JC, Yachimski P (2013). Directional distribution of neoplasia in Barrett's esophagus is not influenced by distance from the gastroesophageal junction. Gastrointestinal Endoscopy. 2013 Jun;77(6):877-82. PMID: 23528657
  18. Francis DO, Rymer JA, Slaughter JC, Choksi Y, Jiramongkolchai P, Ogbeide E, Tran C, Goutte M, Garrett CG, Hagaman D, Vaezi MF (2013). High Economic Burden of Caring for Patients With Suspected Extraesophageal Reflux. American Journal of Gastroenterology. 2013 Jun;108(6):905-11. PMID: 23545710.
  19. Rice NT, Hu Y, Slaughter JC, Ward RM (2013). Pelvic Mesh Complications in Women Before and After the 2011 FDA Public Health Notification. Female Pelvic Medicine & Reconstructive Surgery. 2013 Nov-Dec;19(6):333-8. PMID: 24165446.
  20. Wilson AJ, Liu AY, Roland JT, Adebayo OB, Fletcher SA, Slaughter JC, Saskowski J, Crispens MA, Jones HW, James S, Fadare O, Khabele D. (2013). TR3 modulates platinum resistance in ovarian cancer. Cancer Research. 2013 Aug 1;73(15):4758-69. PMID: 23720056
  21. Martinez-Finley EJ, Chakraborty S, Slaughter JC, and Aschner M (2013). Early-life exposure to methylmercury in wildtype and pdr-1/parkin knockout C. elegans. Neurochemical Research. Aug;38(8):1543-52. PMID: 23609499
  22. Stefanescu BM, Hetu C, Slaughter JC, O'Shea TM, and Shetty AK (2013). A Pilot Study of Biotene OralBalance Gel for Oral Care in Mechanically Ventilated Preterm Neonates. Contemporary Clinical Trials. Jul;35(2):33-9. PMID: 23608625.
  23. Cotton RB, Shah LP, Poole SD, Ehinger NJ, Brown N, Shelton EL, Slaughter JC, Baldwin HS, Paria BC, Reese J (2013). Cimetidine-associated patent ductus arteriosus is mediated via a cytochrome P450 mechanism independent of H2 receptor antagonism. Journal of Molecular and Cellular Cardiology. Jun;59:86-94. PMID: 23454087.
  24. Yuksel ES, Slaughter JC, Mukhtar N, Ochieng M, Sun G, Goutte M, Muddana S, Gaelyn Garrett C, Vaezi MF (2013). An oropharyngeal pH monitoring device to evaluate patients with chronic laryngitis. Neurogastroenterology and Motility. May;25(5):e315-23. PMID: 23495894
  25. Fike CD, Dikalova A, Slaughter JC, Kaplowitz MR, Zhang Y, Aschner JL (2013). Reactive oxygen species reducing strategies improve pulmonary arterial responses to nitric oxide in piglets with chronic hypoxia-induced pulmonary hypertension Antioxidants and Redox Signaling. May 10;18(14):1727-38. PMID: 23244497.
  26. Gowda M, Danford JM, Hu Y, Slaughter JC, Zimmerman CW, Ward RM (2013). Clinical findings associated with bladder trabeculations in women. International Urogynecology Journal. Jul;24(7):1167-71. PMID: 23160872
  27. Noto JM, Gaddy JA, Lee JY, Piazuelo MB, Friedman DB, Colvin CDC, Romero-Gallo J, Suarez G, Loh J, Slaughter JC, Tan S, Morgan DR, Wilson KT, Bravo LE, Correa P, Cover TL, Amieva MR, Peek RM (2013). Iron deficiency accelerates Helicobacter pylori-induced carcinogenesis in rodents and humans. Journal of Clinical Investigation. Jan 2;123(1):479-92. PMID: 23257361.
  28. Kavitt RT, Yuksel ES, Slaughter JC, Garrett CG, Hagaman D, Higginbotham T, Vaezi MF (2013). The Role of Impedance Monitoring in Patients With Extraesophageal Symptoms. The Laryngoscope. Oct;123(10):2463-8. PMID: 23857711
  29. Kavitt RT, Higginbotham T, Slaughter JC, Patel D, Yuksel ES, Lominadze Z, Abou-Ismail A, Pasricha T, Garrett CG, Hagaman D, Vaezi MF (2012). Symptom reports are not reliable during ambulatory reflux monitoring. Am J Gastroenterol. Dec;107(12):1826-32. PMID: 23090349.
  30. Yuksel ES, Higginbotham T, Slaughter JC, Mabary J, Kavitt R, Garrett CG, Vaezi MF (2012). Use of direct endoscopic guided mucosal impedance measurement as a novel technique to diagnose GERD. Clinical Gastroenterology and Hepatology. Dec;107(12):1826-32. PMID: 22642956
  31. Chen JX, OMara PW, Poole SD, Brown N, Ehinger NJ, Slaughter JC, Paria BC, Aschner JL, Reese J (2012). Isoprostanes as physiological mediators of transition to newborn life: Novel mechanisms regulating patency of the term and preterm ductus arteriosus. Pediatric Research. Aug;72(2):122-8. PMID: 22565502
  32. Zhang C, Sherman MP, Prince LS, Bader D, Weitkamp JH, Slaughter JC, McElroy SJ (2012). Paneth cell ablation in the presence of Klebsiella pneumonia induces necrotizing enterocolitis (NEC) like injury in immature murine small intestine. Disease Models and Mechanisms. Jul;5(4):522-32. PMID: 22328592.
  33. Francis DO, Sumner E, Goutte M, Slaughter JC, Garrett CG, Hagaman D, Vaezi M (2012). Feasibility of dual wireless esophageal pH monitoring: randomized blinded sham-controlled trial. Otolaryngol Head Neck Surg. Jul;147(1):91-7. PMID: 2236804
  34. Saritas Yuksel E, Hong SK, Strugala V, Slaughter JC, Goutte M, Garrett CG, Dettmar PW, Vaezi MF. (2012). Rapid Salivary Pepsin Test: Blinded Assessment of Test Performance in GERD. The Laryngoscope. Jun;122(6):1312-6. PMID: 22447277.
  35. Gold KP, Ward RM, Zimmerman CW, Biller DH, McGuinn S, Slaughter JC, Dmochowski RR. (2011). Factors Associated With Exposure of Transvaginally-placed Polypropylene Mesh for Pelvic Organ Prolapse. International Urogynecology Journal. Oct;23(10):1461-6. PMID: 22447037.
  36. Fletcher KC, Goutte M, Slaughter JC, Garrett CG, Vaezi MF (2011). Significance and degree of reflux in patients with primary extraesophageal symptoms. Laryngoscope. Dec;121(12):2561-5. PMID: 22109753
  37. McElroy SJ, Prince LS, Weitkamp JH, Reese J, Slaughter JC, Polk DB. (2011). Tumor Necrosis Factor Receptor 1-Dependent Depletion of Mucus in Immature Small Intestine: A Potential Role in Neonatal Necrotizing Enterocolitis. AJP Gastrointestinal and Livery Physiology. Oct;301(4):G656-66. PMID: 21737776
  38. Slaughter JC, Goutte M, Rymer JA, Oranu AC, Schneider JA, Garrett CG, Hagaman D, Vaezi MF (2011). Caution about Over-Interpretation of Symptom Indices in Reflux Monitoring for Refractory Gastroesophageal Reflux Disease. Clinical Gastroenterology and Hepatology. Oct;9(10):868-74. PMID: 21782769
  39. Francis DO, Goutte M, Slaughter JC, Garrett CG, Hagaman D, Holzman MD, Vaezi MF (2011). Traditional reflux parameters and not impedance monitoring predict outcome post fundoplication in extra-esophageal reflux Laryngoscope. Sep;121(9):1902-9. PMID: 22024842.
  40. Fike CD, Aschner JL, Slaughter JC, Kaplowitz MR, Zhang Y, Pfister SL (2011). Pulmonary arterial responses to reactive oxygen species are altered in newborn piglets with chronic hypoxia-induced pulmonary hypertension Pediatric Research. Aug;70(2):136-41. PMID: 21516056
  41. Nagy TA, Allen SS, Wroblewski LE, Flaherty DK, Slaughter JC, Perez-Perez G, Israel DA, Peek RM (2011). Helicobacter pylori induction of eosinophil migration is mediated by the cag pathogenicity island via microbial-epithelial interactions. American Journal of Pathology. Apr;178(4):1448-52. PMID:21406172
  42. Vaezi MF, Hagaman DD, Slaughter JC, Tanner SB, Duncavage JA, Allocco CT, Sparkman C, Clement LE, Wasden CM, Wirth D, Goutte M, McCafferty BA, Lanza DC (2010). Proton Pump Inhibitor Therapy Improves Symptoms in Post Nasal Drainage. Gastroenterology. 39(6):1887-1893. PMID: 20801120
  43. Fike CD, Pfister S, Slaughter JC, Kaplowitz M, Zhang Y, Zeng H, Frye N, Aschner JL (2010). Protein Complex Formation with Heat Shock Protein 90 (Hsp90) in Chronic Hypoxia-Induced Pulmonary Hypertension in Newborn Piglets. American Journal of Physiology, Heart and Circulatory Physiology. 299: 1190-1204. PMID: 20693398
  44. Vaezi MF, Slaughter JC, Smith BS, Washington MK, Jerome WG, Garret CG, Hagaman D, Goutte M (2010). Dilated Intercellular Space does not Discriminate Controls from Gastroesophageal Reflux Disease or Chronic Laryngitis. Alimentary Pharmacology & Therapeutics. 32 (7) 916-924. PMID: 20735783
  45. Maitre NL, Marshall DD, Goldstein RF, Slaughter JC, Price WA. (2010). Necrotizing enterocolitis in infants with periventricular hemorrhagic infarction: associations and outcomes. Neonatology. 99(2):97-103 PMID: 20664299
  46. Hill ML, Baldwin L, Slaughter JC, Walsh WF, Weitkamp J-H (2010). A Silver Alginate-Coated Dressing to Reduce Peripherally Inserted Central Catheter (PICC) Infections in NICU Patients - a Pilot Randomized Controlled Trial. The Journal of Perinatology. Jul;30(7):469-73. PMID: 20010613
  47. Hong SS, Maltz BE, Coburn LA, Slaughter JC, Chaturvedi R, Schwartz DA, Wilson KT (2010). Increased Serum Levels of L-Arginine in Ulcerative Colitis and Correlation with Disease Severity Inflammatory Bowel Disease. 16(1): 105-111. PMCID: PMC2795785
  48. Brown N, Morrow JD, Slaughter JC, Paria BC, Reese J (2009). Restoration of on-time embryo implantation corrects the timing of parturition in cytosolic phospholipase A2 group IVA deficient mice. Biology of Reproduction. 81 (6): 1131-1138. PMID: 19684335
  49. Maitre NL, Marshall DD, Price W, Slaughter JC, O’Shea TM, Goldstein R (2009). Neurodevelopmental outcomes of infants with unilateral or bilateral periventricular hemorrhagic infarction. Pediatrics. 124(6): E1153-E1160. PMID: 19948617
  50. Slaughter JC, Herring AH, and Thorp JM (2009). A Bayesian Latent Variable Mixture Model for Longitudinal Fetal Growth. Biometrics. 65(4) 1233-1242. PMID: 19432784
  51. Pritchett JM, Aslam M, Slaughter JC, Ness RM, Garrett CG, Vaezi MF (2009). Efficacy of Esophageal Impedance/pH Monitoring in Patients With Refractory Gastroesophageal Reflux Disease, on and off Therapy. Clinical Gastroenterology and Hepatology. 7(7): 743-748. PMID: 19281866
  52. Sun G, Muddana S, Slaughter JC, Vaezi MF (2009). A New pH Catheter for Laryngopharyngeal Reflux: Normal Values. The Laryngoscope. 119(8) 1639-1643. PMID: 19504553
  53. Hartmann KE, McPheeters ML, Biller DH, Ward RM, McKoy JN, Jerome RN, Micucci SR, Meints L, Fisher JA, Scott T, Slaughter JC, Blume JD (2009). Treatment of Overactive Bladder in Women. Evidence Report/Technology Assessment No. 187 (Prepared by the Vanderbilt Evidence-based Practice Center under Contract No. 290-2007-10065-I.) AHRQ Publication No. 09-E017. Rockville, MD: Agency for Healthcare Research and Quality. August. 2009. PMID: 19947666
  54. Johnson JL, Muller KE, Slaughter JC, Gurka MJ, Gribbin MJ, Simpson SL (2009). POWERLIB: SAS/IML Software for Computing Power in Multivariate Linear Models Journal of Statistical Software. 30(5), 1-27.
  55. Falcone MT, Garrett CG, Slaughter JC, Vaezi M (2009). Transnasal esophagoscopy findings: Interspecialty comparion. Otolaryngology-Head and Neck Surgery. 140(6): 812-815. PMID: 19467395
  56. Aschner JL, Zeng H, Kaplowitz MR, Zhang Y, Slaughter JC, Fike CD (2009). Heat shock protein 90 (Hsp90)/eNOS interactions mature with postnatal age in the pulmonary circulation of the piglet. Am J Physiol Lung Cell Mol Physiol. 296(3), 555-564. PMCID: PMC2660212
  57. Fike CD, Slaughter JC, Kaplowitz MR, Zhang Y, and Aschner JL (2008). Reactive oxygen species from NADPH oxidase contribute to altered pulmonary vascular responses in newborn piglets with chronic hypoxia-induced pulmonary hypertension. Lung, Cellular, and Molecular Physiology. 295(5), 881-888. PMCID: PMC2584882
  58. Slaughter JC, Herring AH, and Hartmann KE (2008). Bayesian Modeling of Embryonic Growth Using Latent Variables. Biostatistics, 9(2), 373-89. PMID: 18056115
  59. Schildcrout JS, Sheppard L, Lumley TS, Slaughter JC, Koenig JQ, Shapiro GG (2006). Ambient air pollution and asthma aggravation in children: An eight-city analysis. American Journal of Epidemiology, 164(6), 505-517.
  60. Sheppard L, Slaughter JC, Schildcrout J, Liu S, and Lumley T (2005). Exposure and Measurement Contributions to Estimates of Acute Air Pollution Effects. Journal of Exposure Analysis and Environmental Epidemiology, 15, 366-376.
  61. Slaughter JC, Kim E, Sheppard L, Sullivan JH, Larson TV, Claiborn C (2005). Association between particulate matter and emergency room visits, hospital admissions, and mortality in Spokane, Washington. Journal of Exposure Analysis and Environmental Epidemiology, 15, 153-159.
  62. Slaughter JC, Koenig JQ, Reinhardt TL (Jan 2004). Association between Lung Function and Exposure to Smoke among Firefighters at Prescribed Burns. Journal of Occupational and Environmental Hygiene, 1(1), 45-49.
  63. Slaughter JC, Lumley T, Sheppard L, Koenig JQ, and Shapiro GG (Oct 2003). Effects of Ambient Air Pollution on Symptom Severity and Medication Usage in Children with Asthma. Annals of Allergy, Asthma, and Immunology, 91(4), 346-353.
  64. Kim E, Larson TV, Hopke PK, Slaughter C, Sheppard LE, and Claiborn C (2003). Source Identification of PM2.5 in an Arid Northwest U.S. City by Positive Matrix Factorization. Atmospheric Research, 66, 291-305.
  65. Liu L-JS, Slaughter JC, Larson TV (2002). Comparison of Light Scattering Devices and Impactors for Particulate Measurements in Indoor, Outdoor, and Personal Environments. Environ Sci Technol, 36, 2977-2986.
>
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  1. William S. Bush, Guanhua Chen, Eric S. Torstenson, Marylyn D. Ritchie : LD-Spline: Mapping SNPs on genotyping platforms to genomic regions using patterns of linkage disequilibrium, BioData Mining, 2009, 2:2-7
  2. Rachael J. Bloom, Anna K Khler, Ann L. Collins, Guanhua Chen, Tyrone D. Cannon, Christina Hultman, Patrick F. Sullivan: Comprehensive analysis of copy number variation in monozygotic twins discordant for bipolar disorder or schizophrenia. Schizophrenia Research, 2013, 146(1-3):289-290.
  3. Guanhua Chen, Patrick F. Sullivan, Michael R. Kosorok: Biclustering with heterogenous variance. Proceedings of the National Academy of Sciences, 2013, 110(30): 12253-12258.
  4. Fred A. Wright, ... , Guanhua Chen, ... , Patrick F. Sullivan: Heritability and genomics of gene expression in peripheral blood. Nature Genetics, 2014, 46:430-437.
  5. Jin Szatkiewicz, Colm T. O'Dushlaine, Guanhua Chen, ... , Patrick F. Sullivan: Copy number variation in Schizophrenia in Sweden. Molecular Psychiatry, 2014, 19:762-773

Technical report

  1. Guanhua Chen, Yufeng Liu, Dinggang Shen, Michael R. Kosorok: Composite large margin classifiers with latent subclasses.
  2. Guanhua Chen, Donglin Zeng, Michael R. Kosorok: Personalized dose finding using outcome weighted learning.
  3. Qian Liu, Guanhua Chen, Michael R. Kosorok, Eric Bair: Biclustering Via Sparse Clustering. arxiv:1407.3010

Software/Code

HSSVD: R package that performs biclustering, which allows heterogeneous variance.
 
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Guanhua Chen, DrPH

Vanderbilt University School of Medicine
Department of Biostatistics
2525 West End Avenue, Suite 11000
Nashville, TN  37203-1738
james.c.slaughter at vanderbilt.edu

Phone: 615.322.0439

ChrisSlaughter.JPG

Research Interests

  • Longitudinal data analysis for observational studies
  • Latent variable methods
  • Bayesian statistics
  • Reproductive health applications

Education

  • DrPH in Biostatistics 2007
  • University of North Carolina at Chapel Hill
  • Dissertation: Bayesian Latent Variable Methods for Fetal Growth and Development
  • Advisor: Amy H Herring

  • MS in Biostatistics 2000
  • University of Washington
  • Advisor: Thomas Lumley

  • BS in Cell and Molecular Biology 1998
  • BS in Mathematics 1998
  • Tulane University

Work Experience

  • Assistant Professor 2007-Present
  • Vanderbilt University, Department of Biostatistics

  • Research Scientist 2000-2002
  • UW-EPA NW Research Center for Particulate Matter and Health

Courses Taught

Vanderbilt Collaborations

  • Gastroenterology
  • Neonatology
  • Vaccine Center

Published Papers

  1. Vucovich M, Cotton R, Shelton E, Goettel J, Ehinger N, Poole S, Brown N, Wynn J, Paria B, Slaughter JC, Clark R, Rojas M, Reese J (2014). Aminoglycside-mediated relaxation of the ductus arteriosus in sepsis-associated PDA. American Journal of Physiology - Heart and Circulatory Physiology. Accepted. PMID: 24993047
  2. Chorna O, Solomon JE, Slaughter JC, Stark AR, Maitre NL. Abnormal sensory reactivity in preterm infants during the first year correlates with adverse neurodevelopmental outcomes at 2 years of age (2014). Archives of Disease in Childhood. 2014 Jul 22[ Epub ahead of print]. PMID: 25053637
  3. Maitre NL, Slaughter JC, Aschner JL, Key AP (2014). Hemisphere Differences in Speech-Sound Event-Related Potentials in Intensive Care Neonates: Associations and Predictive Value for Development in Infancy. Journal of Child Neurology. 2013 Jul 17. [Epub ahead of print]. PMID: 23864588
  4. Stouch AN, Zaynagetdinov R, Barham WJ, Stinnett AM, Slaughter JC, Yull FE, Hoffman HM, Blackwell TS, Prince LS. IKK-beta Activity Drives Fetal Lung Macrophage Maturation Along a Non-M1/M2 Paradigm. The Journal of Immunology (2014) Aug 1;193(3):1184-93. PMID 24981452.
  5. Maitre N, Henderson G, Gogliotti S, Pearson J, Simmons A, Wang L, Slaughter JC, Key, A. Feasibility of ERP methodology to evaluate changes in cortical processing after rehabilitation in children with cerebral palsy: a pilot study. Journal of Clinical and Experimental Neuropsychology 2014 Jun 23:1-11. PMID: 24953907
  6. Romano-Keeler J, Moore DJ, Wang C, Brucker RM, Fonnesbeck C, Slaughter JC, Li H, Curran DP, Meng S, Correa H, Lovvorn HN 3rd, Tang YW, Bordenstein S, George AL Jr, Weitkamp JH. (2014). Early life establishment of site-specific microbial communities in the gut.. Gut Microbes. 2014 Mar 1;5(2):192-201. doi: 10.4161/gmic.28442. PMID: 24637795.
  7. Maitre NL, Slaughter JC, Stark AR, Aschner JL, Anderson AW (2014). Validation of a brain MRI relaxometry protocol to measure effects of preterm birth at a flexible postnatal age. BMC Pediatrics. 14:84. doi:10.1186/1471-2431-14-84. PMID: 24678975
  8. Bates JT, Keefer C, Slaughter JC, Kulp D, Schief W, Crowe JE (2014) Escape from neutralization by the respiratory syncytial virus-specific neutralizing monoclonal antibody palivizumab is driven by changes in on-rate of binding to the fusion protein. Virology. 2014 Apr;454-455:139-44. PMID: 24725940
  9. Chorna O, Slaughter JC, Wang L, Stark A, Maitre, NL (2014). A Pacifier-Activated Music Player with motherís voice improves oral feeding in preterm infants Pediatrics. 2014 Mar;133(3):462-8. PMID: 24534413.
  10. Coburn LA, Horst SN, Chaturvedi R, Brown CT , Allaman MM, Scull BP, Singh K, Piazuelo MB, Chitnavis MV, Hodges ME, Rosen MJ, Williams CM, Slaughter JC, Beaulieu DB, Schwartz DA, Wilson KT (2013). High-throughput multi-analyte Luminex profiling implicates eotaxin-1 in ulcerative colitis. PLOS ONE. 2013 Dec 18;8(12):e82300. PMID: 24367513
  11. Casner M, Hoesli SJ, Slaughter JC, Hill M, Weitkamp JH (2014). Incidence of Catheter Related Bloodstream Infections in Neonates Following Removal of Peripherally Inserted Central Venous Catheters. Pediatric Critical Care Medicine. 2014 Jan;15(1):42-8. doi: 10.1097/PCC.0b013e31829f5feb. PMID: 24141656
  12. Yachimski P, Shi C, Slaughter JC, Washington MK (2013). Endoscopic mucosal resection of Barrett's esophagus detects high prevalence of subsquamous intestinal metaplasia. World Journal of Gastrointestinal Endoscopy. 2013 Dec 16;5(12):590-4. PMID: 24368934
  13. Coggins SA, Wynn JL, Hill ML, Slaughter JC, Ozdas-Weitkamp A, Jalloh O, Waitman LR, Carnevale RJ, Weitkamp JH (2013). Use of a computerized C-reactive protein (CRP) based sepsis evaluation in very low birth weight (VLBW) infants: A five-year experience. PLOS ONE. 2013 Nov 11;8(11):e78602. PMID: 24244325.
  14. Maitre NL, Smolinsky C, Slaughter JC, Stark AR. (2013). Adverse neurodevelopmental outcomes after exposure to phenobarbital and levetiracetam for the treatment of neonatal seizures. Journal of Perinatology. 2013 Nov;33(11):841-6. PMID: 24051577
  15. Matire NL, Slaughter JC, Aschner JL (2013). Early prediction of cerebral palsy after neonatal intensive care using motor development trajectories in infancy. Early Human Development. 2013 Oct;89(10):781-6. PMID: 23856349
  16. Gillam-Krakauer M, Cochran CM, Slaughter JC, Polavarapu S, McElroy SJ, Hernanz-Schulman M, Engelhardt B (2013). Correlation of abdominal rSO(2) with superior mesenteric artery velocities in preterm infants. Journal of Perinatology. 2013 Aug;33(8):609-12. PMID: 23392317.
  17. Cassani L, Sumner E, Slaughter JC, Yachimski P (2013). Directional distribution of neoplasia in Barrett's esophagus is not influenced by distance from the gastroesophageal junction. Gastrointestinal Endoscopy. 2013 Jun;77(6):877-82. PMID: 23528657
  18. Francis DO, Rymer JA, Slaughter JC, Choksi Y, Jiramongkolchai P, Ogbeide E, Tran C, Goutte M, Garrett CG, Hagaman D, Vaezi MF (2013). High Economic Burden of Caring for Patients With Suspected Extraesophageal Reflux. American Journal of Gastroenterology. 2013 Jun;108(6):905-11. PMID: 23545710.
  19. Rice NT, Hu Y, Slaughter JC, Ward RM (2013). Pelvic Mesh Complications in Women Before and After the 2011 FDA Public Health Notification. Female Pelvic Medicine & Reconstructive Surgery. 2013 Nov-Dec;19(6):333-8. PMID: 24165446.
  20. Wilson AJ, Liu AY, Roland JT, Adebayo OB, Fletcher SA, Slaughter JC, Saskowski J, Crispens MA, Jones HW, James S, Fadare O, Khabele D. (2013). TR3 modulates platinum resistance in ovarian cancer. Cancer Research. 2013 Aug 1;73(15):4758-69. PMID: 23720056
  21. Martinez-Finley EJ, Chakraborty S, Slaughter JC, and Aschner M (2013). Early-life exposure to methylmercury in wildtype and pdr-1/parkin knockout C. elegans. Neurochemical Research. Aug;38(8):1543-52. PMID: 23609499
  22. Stefanescu BM, Hetu C, Slaughter JC, O'Shea TM, and Shetty AK (2013). A Pilot Study of Biotene OralBalance Gel for Oral Care in Mechanically Ventilated Preterm Neonates. Contemporary Clinical Trials. Jul;35(2):33-9. PMID: 23608625.
  23. Cotton RB, Shah LP, Poole SD, Ehinger NJ, Brown N, Shelton EL, Slaughter JC, Baldwin HS, Paria BC, Reese J (2013). Cimetidine-associated patent ductus arteriosus is mediated via a cytochrome P450 mechanism independent of H2 receptor antagonism. Journal of Molecular and Cellular Cardiology. Jun;59:86-94. PMID: 23454087.
  24. Yuksel ES, Slaughter JC, Mukhtar N, Ochieng M, Sun G, Goutte M, Muddana S, Gaelyn Garrett C, Vaezi MF (2013). An oropharyngeal pH monitoring device to evaluate patients with chronic laryngitis. Neurogastroenterology and Motility. May;25(5):e315-23. PMID: 23495894
  25. Fike CD, Dikalova A, Slaughter JC, Kaplowitz MR, Zhang Y, Aschner JL (2013). Reactive oxygen species reducing strategies improve pulmonary arterial responses to nitric oxide in piglets with chronic hypoxia-induced pulmonary hypertension Antioxidants and Redox Signaling. May 10;18(14):1727-38. PMID: 23244497.
  26. Gowda M, Danford JM, Hu Y, Slaughter JC, Zimmerman CW, Ward RM (2013). Clinical findings associated with bladder trabeculations in women. International Urogynecology Journal. Jul;24(7):1167-71. PMID: 23160872
  27. Noto JM, Gaddy JA, Lee JY, Piazuelo MB, Friedman DB, Colvin CDC, Romero-Gallo J, Suarez G, Loh J, Slaughter JC, Tan S, Morgan DR, Wilson KT, Bravo LE, Correa P, Cover TL, Amieva MR, Peek RM (2013). Iron deficiency accelerates Helicobacter pylori-induced carcinogenesis in rodents and humans. Journal of Clinical Investigation. Jan 2;123(1):479-92. PMID: 23257361.
  28. Kavitt RT, Yuksel ES, Slaughter JC, Garrett CG, Hagaman D, Higginbotham T, Vaezi MF (2013). The Role of Impedance Monitoring in Patients With Extraesophageal Symptoms. The Laryngoscope. Oct;123(10):2463-8. PMID: 23857711
  29. Kavitt RT, Higginbotham T, Slaughter JC, Patel D, Yuksel ES, Lominadze Z, Abou-Ismail A, Pasricha T, Garrett CG, Hagaman D, Vaezi MF (2012). Symptom reports are not reliable during ambulatory reflux monitoring. Am J Gastroenterol. Dec;107(12):1826-32. PMID: 23090349.
  30. Yuksel ES, Higginbotham T, Slaughter JC, Mabary J, Kavitt R, Garrett CG, Vaezi MF (2012). Use of direct endoscopic guided mucosal impedance measurement as a novel technique to diagnose GERD. Clinical Gastroenterology and Hepatology. Dec;107(12):1826-32. PMID: 22642956
  31. Chen JX, OMara PW, Poole SD, Brown N, Ehinger NJ, Slaughter JC, Paria BC, Aschner JL, Reese J (2012). Isoprostanes as physiological mediators of transition to newborn life: Novel mechanisms regulating patency of the term and preterm ductus arteriosus. Pediatric Research. Aug;72(2):122-8. PMID: 22565502
  32. Zhang C, Sherman MP, Prince LS, Bader D, Weitkamp JH, Slaughter JC, McElroy SJ (2012). Paneth cell ablation in the presence of Klebsiella pneumonia induces necrotizing enterocolitis (NEC) like injury in immature murine small intestine. Disease Models and Mechanisms. Jul;5(4):522-32. PMID: 22328592.
  33. Francis DO, Sumner E, Goutte M, Slaughter JC, Garrett CG, Hagaman D, Vaezi M (2012). Feasibility of dual wireless esophageal pH monitoring: randomized blinded sham-controlled trial. Otolaryngol Head Neck Surg. Jul;147(1):91-7. PMID: 2236804
  34. Saritas Yuksel E, Hong SK, Strugala V, Slaughter JC, Goutte M, Garrett CG, Dettmar PW, Vaezi MF. (2012). Rapid Salivary Pepsin Test: Blinded Assessment of Test Performance in GERD. The Laryngoscope. Jun;122(6):1312-6. PMID: 22447277.
  35. Gold KP, Ward RM, Zimmerman CW, Biller DH, McGuinn S, Slaughter JC, Dmochowski RR. (2011). Factors Associated With Exposure of Transvaginally-placed Polypropylene Mesh for Pelvic Organ Prolapse. International Urogynecology Journal. Oct;23(10):1461-6. PMID: 22447037.
  36. Fletcher KC, Goutte M, Slaughter JC, Garrett CG, Vaezi MF (2011). Significance and degree of reflux in patients with primary extraesophageal symptoms. Laryngoscope. Dec;121(12):2561-5. PMID: 22109753
  37. McElroy SJ, Prince LS, Weitkamp JH, Reese J, Slaughter JC, Polk DB. (2011). Tumor Necrosis Factor Receptor 1-Dependent Depletion of Mucus in Immature Small Intestine: A Potential Role in Neonatal Necrotizing Enterocolitis. AJP Gastrointestinal and Livery Physiology. Oct;301(4):G656-66. PMID: 21737776
  38. Slaughter JC, Goutte M, Rymer JA, Oranu AC, Schneider JA, Garrett CG, Hagaman D, Vaezi MF (2011). Caution about Over-Interpretation of Symptom Indices in Reflux Monitoring for Refractory Gastroesophageal Reflux Disease. Clinical Gastroenterology and Hepatology. Oct;9(10):868-74. PMID: 21782769
  39. Francis DO, Goutte M, Slaughter JC, Garrett CG, Hagaman D, Holzman MD, Vaezi MF (2011). Traditional reflux parameters and not impedance monitoring predict outcome post fundoplication in extra-esophageal reflux Laryngoscope. Sep;121(9):1902-9. PMID: 22024842.
  40. Fike CD, Aschner JL, Slaughter JC, Kaplowitz MR, Zhang Y, Pfister SL (2011). Pulmonary arterial responses to reactive oxygen species are altered in newborn piglets with chronic hypoxia-induced pulmonary hypertension Pediatric Research. Aug;70(2):136-41. PMID: 21516056
  41. Nagy TA, Allen SS, Wroblewski LE, Flaherty DK, Slaughter JC, Perez-Perez G, Israel DA, Peek RM (2011). Helicobacter pylori induction of eosinophil migration is mediated by the cag pathogenicity island via microbial-epithelial interactions. American Journal of Pathology. Apr;178(4):1448-52. PMID:21406172
  42. Vaezi MF, Hagaman DD, Slaughter JC, Tanner SB, Duncavage JA, Allocco CT, Sparkman C, Clement LE, Wasden CM, Wirth D, Goutte M, McCafferty BA, Lanza DC (2010). Proton Pump Inhibitor Therapy Improves Symptoms in Post Nasal Drainage. Gastroenterology. 39(6):1887-1893. PMID: 20801120
  43. Fike CD, Pfister S, Slaughter JC, Kaplowitz M, Zhang Y, Zeng H, Frye N, Aschner JL (2010). Protein Complex Formation with Heat Shock Protein 90 (Hsp90) in Chronic Hypoxia-Induced Pulmonary Hypertension in Newborn Piglets. American Journal of Physiology, Heart and Circulatory Physiology. 299: 1190-1204. PMID: 20693398
  44. Vaezi MF, Slaughter JC, Smith BS, Washington MK, Jerome WG, Garret CG, Hagaman D, Goutte M (2010). Dilated Intercellular Space does not Discriminate Controls from Gastroesophageal Reflux Disease or Chronic Laryngitis. Alimentary Pharmacology & Therapeutics. 32 (7) 916-924. PMID: 20735783
  45. Maitre NL, Marshall DD, Goldstein RF, Slaughter JC, Price WA. (2010). Necrotizing enterocolitis in infants with periventricular hemorrhagic infarction: associations and outcomes. Neonatology. 99(2):97-103 PMID: 20664299
  46. Hill ML, Baldwin L, Slaughter JC, Walsh WF, Weitkamp J-H (2010). A Silver Alginate-Coated Dressing to Reduce Peripherally Inserted Central Catheter (PICC) Infections in NICU Patients - a Pilot Randomized Controlled Trial. The Journal of Perinatology. Jul;30(7):469-73. PMID: 20010613
  47. Hong SS, Maltz BE, Coburn LA, Slaughter JC, Chaturvedi R, Schwartz DA, Wilson KT (2010). Increased Serum Levels of L-Arginine in Ulcerative Colitis and Correlation with Disease Severity Inflammatory Bowel Disease. 16(1): 105-111. PMCID: PMC2795785
  48. Brown N, Morrow JD, Slaughter JC, Paria BC, Reese J (2009). Restoration of on-time embryo implantation corrects the timing of parturition in cytosolic phospholipase A2 group IVA deficient mice. Biology of Reproduction. 81 (6): 1131-1138. PMID: 19684335
  49. Maitre NL, Marshall DD, Price W, Slaughter JC, O’Shea TM, Goldstein R (2009). Neurodevelopmental outcomes of infants with unilateral or bilateral periventricular hemorrhagic infarction. Pediatrics. 124(6): E1153-E1160. PMID: 19948617
  50. Slaughter JC, Herring AH, and Thorp JM (2009). A Bayesian Latent Variable Mixture Model for Longitudinal Fetal Growth. Biometrics. 65(4) 1233-1242. PMID: 19432784
  51. Pritchett JM, Aslam M, Slaughter JC, Ness RM, Garrett CG, Vaezi MF (2009). Efficacy of Esophageal Impedance/pH Monitoring in Patients With Refractory Gastroesophageal Reflux Disease, on and off Therapy. Clinical Gastroenterology and Hepatology. 7(7): 743-748. PMID: 19281866
  52. Sun G, Muddana S, Slaughter JC, Vaezi MF (2009). A New pH Catheter for Laryngopharyngeal Reflux: Normal Values. The Laryngoscope. 119(8) 1639-1643. PMID: 19504553
  53. Hartmann KE, McPheeters ML, Biller DH, Ward RM, McKoy JN, Jerome RN, Micucci SR, Meints L, Fisher JA, Scott T, Slaughter JC, Blume JD (2009). Treatment of Overactive Bladder in Women. Evidence Report/Technology Assessment No. 187 (Prepared by the Vanderbilt Evidence-based Practice Center under Contract No. 290-2007-10065-I.) AHRQ Publication No. 09-E017. Rockville, MD: Agency for Healthcare Research and Quality. August. 2009. PMID: 19947666
  54. Johnson JL, Muller KE, Slaughter JC, Gurka MJ, Gribbin MJ, Simpson SL (2009). POWERLIB: SAS/IML Software for Computing Power in Multivariate Linear Models Journal of Statistical Software. 30(5), 1-27.
  55. Falcone MT, Garrett CG, Slaughter JC, Vaezi M (2009). Transnasal esophagoscopy findings: Interspecialty comparion. Otolaryngology-Head and Neck Surgery. 140(6): 812-815. PMID: 19467395
  56. Aschner JL, Zeng H, Kaplowitz MR, Zhang Y, Slaughter JC, Fike CD (2009). Heat shock protein 90 (Hsp90)/eNOS interactions mature with postnatal age in the pulmonary circulation of the piglet. Am J Physiol Lung Cell Mol Physiol. 296(3), 555-564. PMCID: PMC2660212
  57. Fike CD, Slaughter JC, Kaplowitz MR, Zhang Y, and Aschner JL (2008). Reactive oxygen species from NADPH oxidase contribute to altered pulmonary vascular responses in newborn piglets with chronic hypoxia-induced pulmonary hypertension. Lung, Cellular, and Molecular Physiology. 295(5), 881-888. PMCID: PMC2584882
  58. Slaughter JC, Herring AH, and Hartmann KE (2008). Bayesian Modeling of Embryonic Growth Using Latent Variables. Biostatistics, 9(2), 373-89. PMID: 18056115
  59. Schildcrout JS, Sheppard L, Lumley TS, Slaughter JC, Koenig JQ, Shapiro GG (2006). Ambient air pollution and asthma aggravation in children: An eight-city analysis. American Journal of Epidemiology, 164(6), 505-517.
  60. Sheppard L, Slaughter JC, Schildcrout J, Liu S, and Lumley T (2005). Exposure and Measurement Contributions to Estimates of Acute Air Pollution Effects. Journal of Exposure Analysis and Environmental Epidemiology, 15, 366-376.
  61. Slaughter JC, Kim E, Sheppard L, Sullivan JH, Larson TV, Claiborn C (2005). Association between particulate matter and emergency room visits, hospital admissions, and mortality in Spokane, Washington. Journal of Exposure Analysis and Environmental Epidemiology, 15, 153-159.
  62. Slaughter JC, Koenig JQ, Reinhardt TL (Jan 2004). Association between Lung Function and Exposure to Smoke among Firefighters at Prescribed Burns. Journal of Occupational and Environmental Hygiene, 1(1), 45-49.
  63. Slaughter JC, Lumley T, Sheppard L, Koenig JQ, and Shapiro GG (Oct 2003). Effects of Ambient Air Pollution on Symptom Severity and Medication Usage in Children with Asthma. Annals of Allergy, Asthma, and Immunology, 91(4), 346-353.
  64. Kim E, Larson TV, Hopke PK, Slaughter C, Sheppard LE, and Claiborn C (2003). Source Identification of PM2.5 in an Arid Northwest U.S. City by Positive Matrix Factorization. Atmospheric Research, 66, 291-305.
  65. Liu L-JS, Slaughter JC, Larson TV (2002). Comparison of Light Scattering Devices and Impactors for Particulate Measurements in Indoor, Outdoor, and Personal Environments. Environ Sci Technol, 36, 2977-2986.

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