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Jeffrey D. Blume, PhD

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My current research program is focused on three areas: missing data and prediction, mediation analysis, and empirical Bayes methods for the evaluation of surrogate outcomes and for recovering information from published prediction models. Three PhD students work with me in the Statistical Evidence in Data Science (SEDS) lab. Recent work is as follows: we have discovered how to construct a prediction model that minimizes the average out-of-sample prediction error without imputing any missing data; we have developed a new framework for estimating mediation effects that posits just one regression model instead of three; we have extended the Prentice criteria for surrogate outcomes to partial surrogates; and we have discovered how to extract the statistical information behind a published black-box prediction model and use it to improve other prediction models.
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Professor Blume's Curriculum Vitae

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Professor Blume's Curriculum Vitae

 

Webpage on Statistical Evidence

Biostatistics Graduate Program

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Jeffrey D. Blume, PhD

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  My current research program is focused on three areas: missing data and prediction, mediation analysis, and empirical Bayes methods for the evaluation of surrogate outcomes and for recovering information from published prediction models. Three PhD students work with me in the Statistical Evidence in Data Science (SEDS) lab. Recent work is as follows: we have discovered how to construct a prediction model that minimizes the average out-of-sample prediction error without imputing any missing data; we have developed a new framework for estimating mediation effects that posits just one regression model instead of three; we have extended the Prentice criteria for surrogate outcomes to partial surrogates; and we have discovered how to extract the statistical information behind a published black-box prediction model and use it to improve other prediction models.

Professor Blume's Curriculum Vitae

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Webpage on Statistical Evidence

 

Biostatistics Graduate Program

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Jeffrey D. Blume, PhD

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Associate Professor of Biostatistics

Associate Professor of Biomedical Informatics

Director of Graduate Studies

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E-mail: j 'dot' blume 'at' vanderbilt 'dot' edu
Phone: (615) 343-9267
Fax: (615) 343-4924
Assistant to Director of Graduate Studies: Amanda Harding
Vanderbilt University School of Medicine
Department of Biostatistics
2525 West End, Ste. 11000
Nashville, TN 37203
Professor Blume is Associate Professor in the Department of Biostatistics at Vanderbilt University School of Medicine. He is the Director of Graduate Studies, having founded the program after arriving at Vanderbilt in 2008. Professor Blume received his Ph.D. in Biostatistics from the John Hopkins School of Public Health, where he was the recipient of a National Eye Institute Traineeship in Clinical Trials. He has extensive experience in the development, operation, analysis, and methodological aspects of Clinical Trials. Before coming to Vanderbilt, he served as Deputy Director of the Biostatistics and Data Management Center for the American College of Radiology Imaging Network (ACRIN). ACRIN is a NCI funded cooperative group that specializes in clinical trials evaluating new medical imaging technology ( www.acrin.org).
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JB-thumbnail.jpg
E-mail: j 'dot' blume 'at' vanderbilt 'dot' edu
Phone: (615) 343-9267
Fax: (615) 343-4924
Assistant to Director of Graduate Studies: Amanda Harding
Vanderbilt University School of Medicine
Department of Biostatistics
2525 West End, Ste. 11000
Nashville, TN 37203
I am an Associate Professor in the Department of Biostatistics at Vanderbilt University School of Medicine. I am the founding Director of Graduate Studies in Biostatistics at Vanderbilt. I received my Ph.D. in Biostatistics from the John Hopkins School of Public Health, where I was the recipient of a National Eye Institute Traineeship in Clinical Trials. I am the leading expert in likelihood methods for measuring statistical inference and I publish on the foundations of statistical inference. Recent work has led to the development of a “second-generation p-value” that has significantly improved statistical and scientific properties. Throughout my career I have published broadly on the foundations of statistical inference, methodology for analyzing and interpreting receiver operating characteristic curves, clinical trials design and analysis, and neuroimaging. My collaborative experience is quite diverse, with a continuing emphasis on diagnostic and cancer trials, large-scale trials in emergency medicine, translational biomedicine, and radiologic and fMRI studies.
 
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Professor Blume's research has been focused in three areas: (1) Likelihood methods for measuring statistical evidence / foundations of statistical inference, (2) methodology for analyzing and interpreting Receiver Operating Characteristic (ROC) curves, (3) the design, conduct and analysis of Clinical Trials. Professor Blume is working to bring likelihood methods to bear on statistical aspects of the drug/device approval process and to develop likelihood methods that will yield highly efficient adaptive clinical trial designs. However, Dr. Blume is currently supervising 3 PhD candidates in his lab, who are working on an interesting variety of topics: missing data in prediction modeling, false discovery rates, mediation analyses, empirical Bayes methods, Prentice criterion for surrogate endpoints, and re-sampling methods.
>
>
I also have extensive experience in the development, operation, analysis, and methodological aspects of Clinical Trials. Before coming to Vanderbilt, I served as Deputy Director of the Biostatistics and Data Management Center for the American College of Radiology Imaging Network. ACRIN is a NCI funded cooperative group that specializes in clinical trials evaluating new medical imaging technology. I have been the lead statistician for numerous large-scale multicenter trials and regularly chair and serve on data safety monitoring boards. I regularly teach in the Radiological Society of North America’s exclusive Clinical Trial Methodology Workshop for junior faculty.
 
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Professor Blume's Curriculum Vitae

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My current research program is focused on three areas: missing data and prediction, mediation analysis, and empirical Bayes methods for the evaluation of surrogate outcomes and for recovering information from published prediction models. Three PhD students work with me in the Statistical Evidence in Data Science (SEDS) lab. Recent work is as follows: we have discovered how to construct a prediction model that minimizes the average out-of-sample prediction error without imputing any missing data; we have developed a new framework for estimating mediation effects that posits just one regression model instead of three; we have extended the Prentice criteria for surrogate outcomes to partial surrogates; and we have discovered how to extract the statistical information behind a published black-box prediction model and use it to improve other prediction models.

Professor Blume's Curriculum Vitae

 

Biostatistics Graduate Program

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Jeffrey D. Blume, PhD


Associate Professor of Biostatistics

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Associate Professor of Biomedical Informatics

 

Director of Graduate Studies

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E-mail: j 'dot' blume 'at' vanderbilt 'dot' edu
Phone: (615) 343-9267
Fax: (615) 343-4924
Assistant to Director of Graduate Studies: Linda Wilson
Vanderbilt University School of Medicine
Department of Biostatistics
2525 West End, Ste. 11000
Nashville, TN 37203

Professor Blume is Associate Professor in the Department of Biostatistics at Vanderbilt University School of Medicine. He is the Director of Graduate Studies, having founded the program after arriving at Vanderbilt in 2008. Professor Blume received his Ph.D. in Biostatistics from the John Hopkins School of Public Health, where he was the recipient of a National Eye Institute Traineeship in Clinical Trials. He has extensive experience in the development, operation, analysis, and methodological aspects of Clinical Trials. Before coming to Vanderbilt, he served as Deputy Director of the Biostatistics and Data Management Center for the American College of Radiology Imaging Network (ACRIN). ACRIN is a NCI funded cooperative group that specializes in clinical trials evaluating new medical imaging technology ( www.acrin.org).
>
>
JB-thumbnail.jpg
E-mail: j 'dot' blume 'at' vanderbilt 'dot' edu
Phone: (615) 343-9267
Fax: (615) 343-4924
Assistant to Director of Graduate Studies: Amanda Harding
Vanderbilt University School of Medicine
Department of Biostatistics
2525 West End, Ste. 11000
Nashville, TN 37203
Professor Blume is Associate Professor in the Department of Biostatistics at Vanderbilt University School of Medicine. He is the Director of Graduate Studies, having founded the program after arriving at Vanderbilt in 2008. Professor Blume received his Ph.D. in Biostatistics from the John Hopkins School of Public Health, where he was the recipient of a National Eye Institute Traineeship in Clinical Trials. He has extensive experience in the development, operation, analysis, and methodological aspects of Clinical Trials. Before coming to Vanderbilt, he served as Deputy Director of the Biostatistics and Data Management Center for the American College of Radiology Imaging Network (ACRIN). ACRIN is a NCI funded cooperative group that specializes in clinical trials evaluating new medical imaging technology ( www.acrin.org).
 

Professor Blume's research has been focused in three areas: (1) Likelihood methods for measuring statistical evidence / foundations of statistical inference, (2) methodology for analyzing and interpreting Receiver Operating Characteristic (ROC) curves, (3) the design, conduct and analysis of Clinical Trials. Professor Blume is working to bring likelihood methods to bear on statistical aspects of the drug/device approval process and to develop likelihood methods that will yield highly efficient adaptive clinical trial designs. However, Dr. Blume is currently supervising 3 PhD candidates in his lab, who are working on an interesting variety of topics: missing data in prediction modeling, false discovery rates, mediation analyses, empirical Bayes methods, Prentice criterion for surrogate endpoints, and re-sampling methods.
Revision 10
28 Feb 2016 - Main.JeffreyBlume
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Jeffrey D. Blume, PhD


Associate Professor of Biostatistics

Director of Graduate Studies

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Director of Biostatistics Collaboration Center

JB-thumbnail.jpg
E-mail: j 'dot' blume 'at' vanderbilt 'dot' edu
Phone: (615) 343-9267
Fax: (615) 343-4924
Assistant to Director (GS & BCC): Linda Wilson
Vanderbilt University School of Medicine
Department of Biostatistics
2525 West End, Ste. 11000
Nashville, TN 37203
>
>
JB-thumbnail.jpg
E-mail: j 'dot' blume 'at' vanderbilt 'dot' edu
Phone: (615) 343-9267
Fax: (615) 343-4924
Assistant to Director of Graduate Studies: Linda Wilson
Vanderbilt University School of Medicine
Department of Biostatistics
2525 West End, Ste. 11000
Nashville, TN 37203
 
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Professor Blume is Associate Professor in the Department of Biostatistics at Vanderbilt University School of Medicine. He is currently Director of Graduate Studies and Director of the Biostatistics Collaboration Center, both of which he founded after coming to Vanderbilt in the fall of 2008.
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Professor Blume is Associate Professor in the Department of Biostatistics at Vanderbilt University School of Medicine. He is the Director of Graduate Studies, having founded the program after arriving at Vanderbilt in 2008. Professor Blume received his Ph.D. in Biostatistics from the John Hopkins School of Public Health, where he was the recipient of a National Eye Institute Traineeship in Clinical Trials. He has extensive experience in the development, operation, analysis, and methodological aspects of Clinical Trials. Before coming to Vanderbilt, he served as Deputy Director of the Biostatistics and Data Management Center for the American College of Radiology Imaging Network (ACRIN). ACRIN is a NCI funded cooperative group that specializes in clinical trials evaluating new medical imaging technology ( www.acrin.org).
 
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Professor Blume's research is focused in three areas: (1) Likelihood methods for measuring statistical evidence / foundations of statistical inference, (2) methodology for analyzing and interpreting Receiver Operating Characteristic (ROC) curves, (3) the design, conduct and analysis of Clinical Trials. Professor Blume is working to bring likelihood methods to bear on statistical aspects of the drug/device approval process and to develop likelihood methods that will yield highly efficient adaptive clinical trial designs.
>
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Professor Blume's research has been focused in three areas: (1) Likelihood methods for measuring statistical evidence / foundations of statistical inference, (2) methodology for analyzing and interpreting Receiver Operating Characteristic (ROC) curves, (3) the design, conduct and analysis of Clinical Trials. Professor Blume is working to bring likelihood methods to bear on statistical aspects of the drug/device approval process and to develop likelihood methods that will yield highly efficient adaptive clinical trial designs. However, Dr. Blume is currently supervising 3 PhD candidates in his lab, who are working on an interesting variety of topics: missing data in prediction modeling, false discovery rates, mediation analyses, empirical Bayes methods, Prentice criterion for surrogate endpoints, and re-sampling methods.
 
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Professor Blume received his Ph.D. in Biostatistics from the John Hopkins School of Public Health, where he was the recipient of a National Eye Institute Traineeship in Clinical Trials. He has extensive experience in the development, operation, analysis, and methodological aspects of Clinical Trials. Before coming to Vanderbilt, he served as Deputy Director of the Biostatistics and Data Management Center for the American College of Radiology Imaging Network (ACRIN). ACRIN is a NCI funded cooperative group that specializes in clinical trials evaluating new medical imaging technology ( www.acrin.org ).

Professor Blume's Curriculum Vitae

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Professor Blume's Curriculum Vitae

 

Biostatistics Graduate Program

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Biostatistics Collaboration Center (BCC)

Courses

MainCourseBios342
 
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Jeffrey D. Blume, PhD

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Courses

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CourseBios342
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MainCourseBios342
 

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Jeffrey D. Blume, PhD


Associate Professor of Biostatistics

Director of Graduate Studies

Director of Biostatistics Collaboration Center

JB-thumbnail.jpg
E-mail:   j 'dot' blume 'at' vanderbilt 'dot' edu
Phone:  (615) 343-9267
Fax:      (615) 343-4924
Assistant to Director (GS & BCC): Linda Wilson
Vanderbilt University School of Medicine
Department of Biostatistics
S-2323 Medical Center North
Nashville, TN 37232-2158
>
>


Jeffrey D. Blume, PhD


Associate Professor of Biostatistics

Director of Graduate Studies

Director of Biostatistics Collaboration Center

JB-thumbnail.jpg
E-mail: j 'dot' blume 'at' vanderbilt 'dot' edu
Phone: (615) 343-9267
Fax: (615) 343-4924
Assistant to Director (GS & BCC): Linda Wilson
Vanderbilt University School of Medicine
Department of Biostatistics
2525 West End, Ste. 11000
Nashville, TN 37203
 
Deleted:
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<
  Professor Blume is Associate Professor in the Department of Biostatistics at Vanderbilt University School of Medicine. He is currently Director of Graduate Studies and Director of the Biostatistics Collaboration Center, both of which he founded after coming to Vanderbilt in the fall of 2008.

Professor Blume's research is focused in three areas: (1) Likelihood methods for measuring statistical evidence / foundations of statistical inference, (2) methodology for analyzing and interpreting Receiver Operating Characteristic (ROC) curves, (3) the design, conduct and analysis of Clinical Trials. Professor Blume is working to bring likelihood methods to bear on statistical aspects of the drug/device approval process and to develop likelihood methods that will yield highly efficient adaptive clinical trial designs.

Professor Blume received his Ph.D. in Biostatistics from the John Hopkins School of Public Health, where he was the recipient of a National Eye Institute Traineeship in Clinical Trials. He has extensive experience in the development, operation, analysis, and methodological aspects of Clinical Trials. Before coming to Vanderbilt, he served as Deputy Director of the Biostatistics and Data Management Center for the American College of Radiology Imaging Network (ACRIN). ACRIN is a NCI funded cooperative group that specializes in clinical trials evaluating new medical imaging technology ( www.acrin.org ).
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Professor Blume's Curriculum Vitae

Biostatistics Graduate Program

Biostatistics Collaboration Center (BCC)

Courses

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CourseBios342
 
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CourseBios342
 

META FILEATTACHMENT attachment="JBlume_cv_Sept11.pdf" attr="" comment="" date="1320966744" name="JBlume_cv_Sept11.pdf" path="JBlume_cv_Sept11.pdf" size="184748" stream="IO::File=GLOB(0x9597538)" tmpFilename="/tmp/E0tHEpcgvU" user="JeffreyBlume" version="1"
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Revision 7
26 Apr 2013 - Main.JohnBock
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META TOPICPARENT name="TWikiUsers"


Jeffrey D. Blume, PhD


Associate Professor of Biostatistics

Director of Graduate Studies

Director of Biostatistics Collaboration Center

JB-thumbnail.jpg
E-mail:   j 'dot' blume 'at' vanderbilt 'dot' edu
Phone:  (615) 343-9267
Fax:      (615) 343-4924
Assistant to Director (GS & BCC): Linda Wilson
Vanderbilt University School of Medicine
Department of Biostatistics
S-2323 Medical Center North
Nashville, TN 37232-2158
Revision 6
05 Jan 2012 - Main.NateMercaldo
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META TOPICPARENT name="TWikiUsers"


Jeffrey D. Blume, PhD


Associate Professor of Biostatistics

Director of Graduate Studies

Director of Biostatistics Collaboration Center

JB-thumbnail.jpg
E-mail:   j 'dot' blume 'at' vanderbilt 'dot' edu
Phone:  (615) 343-9267
Fax:      (615) 343-4924
Assistant to Director (GS & BCC): Linda Wilson
Vanderbilt University School of Medicine
Department of Biostatistics
S-2323 Medical Center North
Nashville, TN 37232-2158
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Biostatistics Graduate Program

Biostatistics Collaboration Center (BCC)

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Courses

CourseBios342

 
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Jeffrey D. Blume, PhD

Associate Professor of Biostatistics

Director of Graduate Studies

Director, Biostatistics Collaboration Center

JB-thumbnail.jpg
E-mail:   j 'dot' blume 'at' vanderbilt 'dot' edu
Phone:  615-343-9267
Fax:      615-343-4924
Assistant: None
Vanderbilt University School of Medicine
Department of Biostatistics
S-2323 Medical Center North
Nashville, TN 37232-2158
>
>


Jeffrey D. Blume, PhD


Associate Professor of Biostatistics

Director of Graduate Studies

Director of Biostatistics Collaboration Center

JB-thumbnail.jpg
E-mail:   j 'dot' blume 'at' vanderbilt 'dot' edu
Phone:  (615) 343-9267
Fax:      (615) 343-4924
Assistant to Director (GS & BCC): Linda Wilson
Vanderbilt University School of Medicine
Department of Biostatistics
S-2323 Medical Center North
Nashville, TN 37232-2158
 

Professor Blume is Associate Professor in the Department of Biostatistics at Vanderbilt University School of Medicine. He is currently Director of Graduate Studies and Director of the Biostatistics Collaboration Center, both of which he founded after coming to Vanderbilt in the fall of 2008.
Changed:
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Professor Blume's research is focused in three areas: (1) Likelihood methods for measuring statistical evidence, (2) methodology for analyzing and interpreting Receiver Operating Characteristic (ROC) curves, (3) the design, conduct and analysis of Clinical Trials. Professor Blume is working to bring likelihood methods to bear on statistical aspects of the drug/device approval process and to develop likelihood methods that will yield highly efficient adaptive clinical trial designs.
>
>
Professor Blume's research is focused in three areas: (1) Likelihood methods for measuring statistical evidence / foundations of statistical inference, (2) methodology for analyzing and interpreting Receiver Operating Characteristic (ROC) curves, (3) the design, conduct and analysis of Clinical Trials. Professor Blume is working to bring likelihood methods to bear on statistical aspects of the drug/device approval process and to develop likelihood methods that will yield highly efficient adaptive clinical trial designs.
 

Professor Blume received his Ph.D. in Biostatistics from the John Hopkins School of Public Health, where he was the recipient of a National Eye Institute Traineeship in Clinical Trials. He has extensive experience in the development, operation, analysis, and methodological aspects of Clinical Trials. Before coming to Vanderbilt, he served as Deputy Director of the Biostatistics and Data Management Center for the American College of Radiology Imaging Network (ACRIN). ACRIN is a NCI funded cooperative group that specializes in clinical trials evaluating new medical imaging technology ( www.acrin.org ).
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  • Name: Jeffrey Blume
  • Email: j 'dot' blume 'at' vanderbilt 'dot' edu
  • Phone Number: 615-343-9267
  • Comment:
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Professor Blume is Associate Professor in the Department of Biostatistics at Vanderbilt University School of Medicine. He is currently Director of Graduate Studies and Director of the Biostatistics Collaboration Center, both of which he founded after coming to Vanderbilt in the fall of 2008.
 
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Professor Blume's research is focused in three areas: (1) Likelihood methods for measuring statistical evidence, (2) methodology for analyzing and interpreting Receiver Operating Characteristic (ROC) curves, (3) the design, conduct and analysis of Clinical Trials. Professor Blume is working to bring likelihood methods to bear on statistical aspects of the drug/device approval process and to develop likelihood methods that will yield highly efficient adaptive clinical trial designs.

Professor Blume received his Ph.D. in Biostatistics from the John Hopkins School of Public Health, where he was the recipient of a National Eye Institute Traineeship in Clinical Trials. He has extensive experience in the development, operation, analysis, and methodological aspects of Clinical Trials. Before coming to Vanderbilt, he served as Deputy Director of the Biostatistics and Data Management Center for the American College of Radiology Imaging Network (ACRIN). ACRIN is a NCI funded cooperative group that specializes in clinical trials evaluating new medical imaging technology ( www.acrin.org ).

Professor Blume's Curriculum Vitae

Biostatistics Graduate Program

Biostatistics Collaboration Center (BCC)

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  • Name: Jeffrey Blume
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  • Email: j 'dot' blume 'at' vanderbilt 'dot' edu
 
  • Phone Number: 615-343-9267
  • Comment:
 
 
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